Comparison of ΔFVC between patients with allergic rhinitis with airway hypersensitivity and patients with mild asthma
Comparison of ΔFVC between patients with allergic rhinitis with airway hypersensitivity and patients with mild asthma
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DOI：
10.1016/s1081-1206(10)60684-9
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发表时间：
2007-02-01
影响因子：
5.9
通讯作者：
Koh, Young Yull
中科院分区：
文献类型：
--
作者：
Choi, Sun Hee;Kim, Do Kyun;Koh, Young Yull
Background: In asthmatic individuals, airway sensitivity and maximal airway response are increased. Airway sensitivity is usually evaluated by measuring the provocation concentration of inhaled methacholine or histamine that causes a decrease in forced expiratory volume in 1 second of 20% (PC20). The percentage decrease in forced vital capacity at the PC20 (Delta FVC) has been proposed as a surrogate marker for maximal airway response. Individuals with allergic rhinitis and no clinical evidence of asthma frequently exhibit airway hypersensitivity.Objective: To compare the Delta FVC between patients with allergic rhinitis and mild asthmatic patients with a similar degree of airway hypersensitivity.Methods: A retrospective analysis of methacholine challenge test data from 72 children with allergic rhinitis and airway hypersensitivity (methacholine PC20
