Lesions of the cerebellar interpositus nucleus abolish both nictitating membrane and eyelid EMG conditioned responses.
Lesions of the cerebellar interpositus nucleus abolish both nictitating membrane and eyelid EMG conditioned responses.
复制标题
小脑间核的损伤会消除瞬膜和眼睑肌电图条件反应。
DOI：
10.1016/0006-8993(90)91419-h
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发表时间：
1990
期刊：
影响因子：
2.9
通讯作者：
Kanzawa,SA
中科院分区：
文献类型：
--
作者：
Lavond,DG;Logan,CG;Sohn,JH;Garner,WD;Kanzawa,SA
在经典的条件反射过程中，测量了家兔的瞬膜伸展和眼睑肌电活动。这两项措施高度相关。在试验中，眼睑肌电图活动比瞬膜延伸更早达到学习标准。在一项试验中，眼睑肌电图先于瞬膜延伸，并且比瞬膜延伸更稳健。损伤家兔小脑间位核，然后训练26天。音调单独试验的详细分析表明，病变废除了两项措施的条件反射。这些数据证实，条件反应被取消的小脑间位核的损害。
Both nictitating membrane extension and eyelid EMG activity were measured during classical conditioning of rabbits to tone-airpuff pairings. Both measures were highly correlated. Over trials, learning criterion was met earlier with eyelid EMG activity than with nictitating membrane extension. Within a trial, eyelid EMG preceded and was more robust than nictitating membrane extension. The rabbits were lesioned in the cerebellar interpositus nucleus and then trained for up to 26 days. Detailed analyses of tone alone trials demonstrate that the lesion abolished conditioned responses for both measures. These data confirm that conditioned responses are abolished by lesion of the cerebellar interpositus nucleus.