Total Iron Absorption by Young Women from Iron-Biofortified Pearl Millet Composite Meals Is Double That from Regular Millet Meals but Less Than That from Post-Harvest Iron-Fortified Millet Meals
Total Iron Absorption by Young Women from Iron-Biofortified Pearl Millet Composite Meals Is Double That from Regular Millet Meals but Less Than That from Post-Harvest Iron-Fortified Millet Meals
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DOI：
10.3945/jn.113.176826
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发表时间：
2013-09-01
影响因子：
4.2
通讯作者：
Hurrell, Richard F.
中科院分区：
文献类型：
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作者：
Cercamondi, Colin I.;Egli, Ines M.;Hurrell, Richard F.
珍珠谷子(Pennisetum Glucum)的铁生物强化是解决发展中国家谷子消费社区缺铁(ID)的一种有前途的方法。为了评价铁生物强化小米与普通小米和收获后强化铁小米相比提供额外生物有效铁的潜力，对20名边缘铁营养状况的贝宁妇女进行了铁吸收研究。以普通铁、铁生物强化小米粉或采后铁强化珍珠小米粉为基础，配以叶菜酱或秋葵酱作为复合试验餐，喂养5d，以稳定铁同位素掺入红细胞铁吸收率为指标。以普通铁小米为基础的试验餐的铁吸收分数(7.5%)与铁生物强化小米粉的铁吸收分数(7.5%；P=1)没有差别，导致以铁生物强化小米为基础的膳食对全铁的吸收更高(1125vs.527mUg；P<；0.0001)。收获后铁强化小米粉的铁吸收分数(10.4%)高于普通铁和铁生物强化小米粉(P<；0.05和P<；0.01)，导致收获后铁强化小米粉对全铁的吸收较高(分别为1500mg；P<；0.0001和P<；0.05)。结果表明，食用铁生物强化谷子可以使吸收的铁增加一倍，尽管生物强化谷子对铁的吸收分数低于强化谷子，但在小米消费人群中，铁生物强化谷子应该是非常有效的。
Iron biofortification of pearl millet (Pennisetum glaucum) is a promising approach to combat iron deficiency (ID) in the millet-consuming communities of developing countries. To evaluate the potential of iron-biofortified millet to provide additional bioavailable iron compared with regular millet and post-harvest iron-fortified millet, an iron absorption study was conducted in 20 Beninese women with marginal iron status. Composite test meals consisting of millet paste based on regular-iron, iron-biofortified, or post-harvest iron-fortified pearl millet flour accompanied by a leafy vegetable sauce or an okra sauce were fed as multiple meals for 5 d. Iron absorption was measured as erythrocyte incorporation of stable iron isotopes. Fractional iron absorption from test meals based on regular-iron millet (7.5%) did not differ from iron-biofortified millet meals (7.5%; P = 1.0), resulting in a higher quantity of total iron absorbed from the meals based on iron-biofortified millet (1125 vs. 527 mu g; P < 0.0001). Fractional iron absorption from post-harvest iron-fortified millet meals (10.4%) was higher than from regular-iron and iron-biofortified millet meals (P < 0.05 and P < 0.01, respectively), resulting in a higher quantity of total iron absorbed from the post-harvest iron-fortified millet meals (1500 mu g; P < 0.0001 and P < 0.05, respectively). Results indicate that consumption of iron-biofortified millet would double the amount of iron absorbed and, although fractional absorption of iron from biofortification is less than that from fortification, iron-biofortified millet should be highly effective in combatting ID in millet-consuming populations.