Electron-poor benzonitriles as labile, stabilizing ligands in asymmetric catalysis
Electron-poor benzonitriles as labile, stabilizing ligands in asymmetric catalysis
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DOI：
10.1021/ol017218q
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发表时间：
2002-03-07
期刊：
影响因子：
5.2
通讯作者：
Gagné, MR
中科院分区：
文献类型：
--
作者：
Becker, JJ;Van Orden, LJ;Gagné, MR
手性钯催化剂[（S）-MeObiphep）Pd（NCAr）（2）（SbF 6）（2），（S）-4c]已被开发用于各种不对称转化。（S）-4c是实验室稳定的，并且对于Diels-桤木、杂-Diels-桤木和乙醛酸酯-烯反应具有与无腈刘易斯酸催化剂相当的活性。
[GRAPHICS]A chiral palladium catalyst [(S)-MeObiphep)Pd(NCAr)(2)(SbF6)(2), (S)-4c], has been developed for a variety of asymmetric transformations. (S)-4c is bench-stable and has activity comparable to that of the nitrile free Lewis acid catalyst for Diels-Alder, hetero-Diels-Alder, and glyoxylate-ene reactions.