Vesicle coating and uncoating: controlling the formation of large COPII-coated carriers.
Vesicle coating and uncoating: controlling the formation of large COPII-coated carriers.
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DOI：
10.3410/b1-65
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发表时间：
2009-08-26
期刊：
影响因子：
--
通讯作者：
Stephens DJ
中科院分区：
文献类型：
--
作者：
Townley AK;Stephens DJ
现在已相当详细地定义了形成包被囊泡的基本机制。本文重点介绍了我们对从内质网输出大分子货物（例如前胶原）问题的理解的最新进展，并讨论了这对细胞和组织组织以及人类疾病的影响。
The basic mechanisms underlying the formation of coated vesicles are now defined in considerable detail. This article highlights recent developments in our understanding of the problem of exporting large macromolecular cargo such as procollagen from the endoplasmic reticulum and discusses the implications that this has for cell and tissue organisation and human disease.