PREDICTING ANGIOGRAPHY-INDUCED ACUTE RENAL-FUNCTION IMPAIRMENT - CLINICAL RISK MODEL
PREDICTING ANGIOGRAPHY-INDUCED ACUTE RENAL-FUNCTION IMPAIRMENT - CLINICAL RISK MODEL
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DOI：
10.2214/ajr.141.5.1027
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发表时间：
1983-01-01
影响因子：
5
通讯作者：
ROE, DJ
中科院分区：
文献类型：
--
作者：
COCHRAN, ST;WONG, WS;ROE, DJ
患者（266）在肾血管造影后接受了急性肾功能损伤的评估。 45 人 (16.9%) 的血清肌酐 (sCr) 水平显着升高，6 人出现少尿或无尿，1 人需要永久透析。年龄、蛋白尿、基线 sCr 异常、Renografin 76 的使用以及既往肾病是该系列中的 5 个独立危险因素。比值比分析确定存在给定危险因素时发生急性肾功能不全的相对风险（即可能性）。患有潜在肾脏疾病的患者发生 sCr 短暂升高的可能性是没有肾脏疾病的患者的 6.6 倍。设计了一种临床测试模型，根据存在的危险因素的数量来预测特定个体在肾血管造影后发生急性肾功能不全的可能性。证明了一种关系；存在的因素越多，患者患急性肾功能不全的可能性就越大。
Patients (266) were evaluated for development of acute renal function impairment after renal angiography. Forty-five (16.9%) had a significant increase in serum level of creatinine (sCr), 6 developed oliguiria or anuria, and 1 required permanent dialysis. Age, proteinuria, abnormal baseline sCr, use of Renografin 76, and preexisting renal disease were the 5 independent risk factors in the series. An odds-ratio analysis establishes the relative risk (i.e., likelihood) of developing acute renal insufficiency when a given risk factor is present. Patients with underlying renal disease were 6.6 times more likely to develop a transient increase in sCr than those with no renal disease. A clinical test model was devised to predict the likelihood that a given individual would develop acute renal insufficiency after renal angiography on the basis of the number of risk factors present. A relation was demonstrated; the more factors present, the more likely it becomes that a patient will develop acute renal insufficiency.