Thio-urethane oligomers improve the properties of light-cured resin cements.
Thio-urethane oligomers improve the properties of light-cured resin cements.
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DOI：
10.1016/j.dental.2015.02.008
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发表时间：
2015-05
期刊：
影响因子：
--
通讯作者：
Pfeifer CS
中科院分区：
文献类型：
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作者：
Bacchi A;Consani RL;Martim GC;Pfeifer CS
通过将1，6-己二醇-二异氰酸酯（脂肪族）与季戊四醇四-3-巯基丙酸酯（PETMP）或1，3-双（1-异氰酸基-1-甲基乙基）苯（芳香族）与正-三-3-巯基丙酸酯（TMP）以1：2的异氰酸酯：硫醇混合，留下侧硫醇，合成了硫代-正-将低聚物以10-30 phr加入到BisGMA-UDMA-TEGDMA（5：3：2，BUT）中。加入25wt%硅烷化无机填料。还用10-20 phr的芳族低聚物评价了商业水泥（Relyx Veneer，3 M-ESPE）。使用近红外跟踪甲基丙烯酸酯转化率（DC）和聚合速率（Rpmax）。在三点弯曲（ISO 4049）中评价机械性能的弯曲强度/模量（FS/FM和韧性），并在缺口试样（ASTM标准E399-90）中评价断裂韧性（KIC）。在Bioman上测量聚合应力（PS）。体积收缩率（VS，%）用粘结盘技术测量。采用ANOVA/Tukey检验（α=5%）分析结果。在一般情况下，对于BUT水泥，在弯曲的转化率和机械性能的增加与添加硫代氨基甲酸酯低聚物的选定的组。芳香族版本导致比脂肪族更大的FS/FM。实验组的断裂韧性增加了两倍（从1.17±0.36增加到约3.23±0.22 MPa.m1/2）。Rpmax随着硫代巴比妥的加入而降低，但玻璃化点与对照组无统计学差异。两种低聚物的VS和PS均降低。对于商品水泥，20 phr的低聚物增加DC，玻璃化，降低Rpmax，也显着增加KIC，并减少PS和FM。硫代氨基甲酸酯低聚物显示出有利地改性常规的二甲基丙烯酸酯网络。聚合应力的显着降低，同时实现了转化率和断裂韧性增加。
Thio-urethanes were synthesized by combining 1,6-Hexanediol-diissocyante (aliphatic) with pentaerythritol tetra-3-mercaptopropionate (PETMP) or 1,3-bis(1-isocyanato-1-methylethyl)benzene (aromatic) with trimethylol-tris-3-mercaptopropionate (TMP), at 1:2 isocyanate:thiol, leaving pendant thiols. Oligomers were added at 10–30 phr to BisGMA-UDMA-TEGDMA (5:3:2, BUT). 25wt% silanated inorganic fillers were added. Commercial cement (Relyx Veneer, 3M-ESPE) was also evaluated with 10–20 phr of aromatic oligomer. Near-IR was used to follow methacrylate conversion (DC) and rate of polymerization (Rpmax). Mechanical properties were evaluated in three-point bending (ISO 4049) for flexural strength/modulus (FS/FM, and toughness), and notched specimens (ASTM Standard E399-90) for fracture toughness (KIC). Polymerization stress (PS) was measured on the Bioman. Volumetric shrinkage (VS, %) was measured with the bonded disk technique. Results were analyzed with ANOVA/Tukey’s test (α=5%). In general terms, for BUT cements, conversion and mechanical properties in flexure increased for selected groups with the addition of thio-urethane oligomers. The aromatic versions resulted in greater FS/FM than aliphatic. Fracture toughness increased by twofold in the experimental groups (from 1.17±0.36 to around 3.23±0.22 MPa.m1/2). Rpmax decreased with the addition of thio-urethanes, though the vitrification point was not statistically different from the control. VS and PS decreased with both oligomers. For the commercial cement, 20 phr of oligomer increased DC, vitrification, reduced Rpmax and also significantly increased KIC, and reduced PS and FM. Thio-urethane oligomers were shown to favorably modify conventional dimethacrylate networks. Significant reductions in polymerization stress were achieved at the same time conversion and fracture toughness increased.