The universal existence of myodural bridge in mammals: an indication of a necessary function
The universal existence of myodural bridge in mammals: an indication of a necessary function
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哺乳动物中普遍存在肌硬膜桥：这是一种必要功能的标志。
DOI：
10.1038/s41598-017-06863-z
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发表时间：
2017-08-15
影响因子：
4.6
通讯作者：
Sui, Hong-Jin
中科院分区：
文献类型：
--
作者：
Zheng, Nan;Yuan, Xiao-Ying;Sui, Hong-Jin
在人类研究中，文献将“肌硬膜桥”描述为连接枕下肌肉组织和脊髓硬膜的致密纤维组织。现在，“肌硬膜桥”这一概念被视为一种确切的解剖结构，可能对人体的关键生理功能至关重要，并且可能也存在于其他哺乳动物中。为了确定“肌硬膜桥”在其他哺乳动物中的存在，并为功能研究奠定基础，我们对五个不同哺乳动物目的代表动物进行了研究。基于解剖、P45塑化切片和组织学切片，我们发现一种致密纤维组织通过寰枕背侧间隙连接头后小直肌和脊髓硬膜，有时借助寰枕后膜，有时不借助。这些观察到的结缔组织与先前在人类中描述的“肌硬膜桥”非常相似。我们提出，“肌硬膜桥”作为一种进化上保守的结构，存在于许多其他哺乳动物中。此外，我们认为“肌硬膜桥”可能是哺乳动物中的同源器官。因此，这项研究可以为我们理解“肌硬膜桥”的生理意义，特别是在人类中的生理意义提供见解。
The "myodural bridge" was described in literatures as a dense fibrous tissue connecting the suboccipital musculature with the spinal dura mater in human studies. Now the concept of "myodural bridge" was perceived as an exact anatomical structure presumably essential for critical physiological functions in human body, and might exist in other mammals as well. To determine the existence of the "myodural bridge" in other mammals and to lay a foundation for the functional study, we examined representatives in five different mammalian orders. Based on the anatomical dissections, P45 plastinated sections and histological sections, we found that a dense fibrous tissue connected the rectus capitisdorsalis minor and the spinal dura mater through the dorsal atlanto-occipital interspace with or without the medium of the posterior atlanto-occipital membrane. These observed connective tissues were very similar to the "myodural bridge" previously described in humans. We proposed that the "myodural bridge", as an evolutionally conserved structure, presents in many other mammals. Moreover, we believed that the "myodural bridge" might be a homologous organ in mammals. Thus, this study could provide an insight for our understanding the physiological significance of the "myodural bridge", especially in human.