Role of the Stria Vascularis in the Pathogenesis of Sensorineural Hearing Loss: A Narrative Review.
Role of the Stria Vascularis in the Pathogenesis of Sensorineural Hearing Loss: A Narrative Review.
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血管纹在感音神经性听力损失发病机制中的作用：叙述回顾
DOI：
10.3389/fnins.2021.774585
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发表时间：
2021
影响因子：
4.3
通讯作者：
Xiao H
中科院分区：
文献类型：
--
作者：
Yu W;Zong S;Du P;Zhou P;Li H;Wang E;Xiao H
感觉神经性听力损失是由内耳异常引起的一种常见的感觉障碍。血管纹被认为是耳蜗的主要结构，可独立退化并影响听力损失的程度。本文综述了血管纹在不同病因引起的感音神经性听力损失发病机制中的作用，重点从分子事件和信号通路两方面进行了综述，并进一步尝试在细胞和分子生物学水平上探讨其潜在机制。此外，还讨论了该领域的不足和局限性。随着科学技术的飞速发展，充分了解血管纹在感音神经性听力损失发病机制中的作用，为感音神经性听力损失的预防、早期诊断和改进治疗提供了新的契机。
Sensorineural hearing loss is a common sensory impairment in humans caused by abnormalities in the inner ear. The stria vascularis is regarded as a major cochlear structure that can independently degenerate and influence the degree of hearing loss. This review summarizes the current literature on the role of the stria vascularis in the pathogenesis of sensorineural hearing loss resulting from different etiologies, focusing on both molecular events and signaling pathways, and further attempts to explore the underlying mechanisms at the cellular and molecular biological levels. In addition, the deficiencies and limitations of this field are discussed. With the rapid progress in scientific technology, new opportunities are arising to fully understand the role of the stria vascularis in the pathogenesis of sensorineural hearing loss, which, in the future, will hopefully lead to the prevention, early diagnosis, and improved treatment of sensorineural hearing loss.
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影响因子：
3.3
作者：
Chen J;Zhao HB
通讯作者：
Zhao HB
影响因子：
2.8
作者：
Dufek, Brianna;Meehan, Daniel T.;Cosgrove, Dominic
通讯作者：
Cosgrove, Dominic
影响因子：
2.1
作者：
Aminpour, S;Tinling, SP;Brodie, HA
通讯作者：
Brodie, HA
DOI：
10.1016/j.ijporl.2005.11.011
发表时间：
2006-05-01
影响因子：
1.5
作者：
Ahmet, A;Orhan, A;Akyol, M
通讯作者：
Akyol, M
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影响因子：
2.3
作者：
Han WJ;Shi XR;Nuttall A
通讯作者：
Nuttall A