Three-Dimensional Wax Patterning of Paper Fluidic Devices
Three-Dimensional Wax Patterning of Paper Fluidic Devices
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DOI：
10.1021/la501212b
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发表时间：
2014-06-17
期刊：
影响因子：
3.9
通讯作者：
Crooks, Richard M.
中科院分区：
文献类型：
--
作者：
Renault, Christophe;Koehne, Jessica;Crooks, Richard M.
本文描述了一种微流控纸基分析装置(MUPAD)的三维蜡模制作方法。该方法植根于纸中蜡传输的基本细节，并提供了一种简单的方法来制造复杂的通道结构，如半通道和全封闭通道。我们发现，使用半通道而不是普通的开放通道可以用一半的纸来制作三维MU垫。我们还提供了证据，证明完全封闭的通道有效地与外部环境隔离，降低了污染风险，简化了设备的处理，并减缓了溶剂的蒸发。
In this paper we describe a method for three-dimensional wax patterning of microfluidic paper-based analytical devices (mu PADs). The method is rooted in the fundamental details of wax transport in paper and provides a simple way to fabricate complex channel architectures such as hemichannels and fully enclosed channels. We show that three-dimensional mu PADs can be fabricated with half as much paper by using hemichannels rather than ordinary open channels. We also provide evidence that fully enclosed channels are efficiently isolated from the exterior environment, decreasing contamination risks, simplifying the handling of the device, and slowing evaporation of solvents.