Complete nucleotide sequence of the temperate bacteriophage LBR48, a new member of the family Myoviridae
Complete nucleotide sequence of the temperate bacteriophage LBR48, a new member of the family Myoviridae
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DOI：
10.1007/s00705-010-0841-7
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发表时间：
2011-02-01
影响因子：
2.7
通讯作者：
Chang, Hyo Ihl
中科院分区：
文献类型：
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作者：
Jang, Se Hwan;Yoon, Bo Hyun;Chang, Hyo Ihl
LBR48（一种由短乳杆菌溶原菌株诱导的温带噬菌体）的完整基因组序列长 48,211 个核苷酸，包含 90 个假定的开放阅读框。根据显微镜分析和核酸序列测定获得的结构特征，噬菌体LBR48可归类为肌病毒科的成员。基因组分析显示，尽管核苷酸序列相似性较低，但先前报道的来自乳酸菌的管病毒科噬菌体的基因顺序是保守的。对附着位点的分析揭示了 15 个核苷酸长的核心序列。
The complete genomic sequence of LBR48, a temperate bacteriophage induced from a lysogenic strain of Lactobacillus brevis, was found to be 48,211 nucleotides long and to contain 90 putative open reading frames. Based on structural characteristics obtained from microscopic analysis and nucleic acid sequence determination, phage LBR48 can be classified as a member of the family Myoviridae. Analysis of the genome showed the conserved gene order of previously reported phages of the family Siphoviridae from lactic acid bacteria, despite low nucleotide sequence similarity. Analysis of the attachment sites revealed 15-nucleotide-long core sequences.