Pregnancy Recruitment for Population Research: the National Children's Study Vanguard Experience in Wayne County, Michigan

Pregnancy Recruitment for Population Research: the National Children's Study Vanguard Experience in Wayne County, Michigan
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DOI:
10.1111/ppe.12047
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发表时间:
2013-05-01
影响因子:
2.8
通讯作者:
Paneth, Nigel
Paneth, Nigel
中科院分区:
医学3区
文献类型:
--
作者:
Kerver, Jean M.;Elliott, Michael R.;Paneth, Nigel

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为了获得怀孕的概率样本,2009年,国家儿童研究在随机选择的县的随机选择的社区进行了挨家挨户的招募。2011年,在美国10个县进行了一项实验,其中保持了两阶段地理样本,但参与者是在产前护理提供者办公室招募的。我们描述了我们在密歇根州韦恩县以这种方式招募孕妇的经验,该县地理上符合条件的妇女参加了147个产前护理机构,仅占该县怀孕总数的2%。方法在产前护理办公室筛选地址合格性后,我们使用了三部分招募过程:(1)提供者获得我们联系合格患者的许可,(2)临床研究人员在临床环境中向妇女描述研究,(3)调查研究人员访问家庭同意并采访合格妇女。结果我们筛选了34065地址在67个供应商设置找到215个合格的妇女。提供者获得了81.4%符合条件的妇女的研究接触许可,其中92.5%同意家访。所有家访的妇女都同意,净入学率为75%。根据出生证明,我们估计有30%符合条件的县孕妇被招募,在最后的招募月份达到4050%。结论:我们招募了一个高比例的怀孕确定在一个广泛的横截面的供应商办公室。尽管如此,由于时间和资源的限制,我们只能招募一小部分符合地理条件的孕妇。我们的经验表明,通过对提供者而不是家庭进行抽样,可以更有效地实现研究中的怀孕概率抽样。
Background To obtain a probability sample of pregnancies, the National Children's Study conducted door-to-door recruitment in randomly selected neighbourhoods in randomly selected counties in 200910. In 2011, an experiment was conducted in 10 US counties, in which the two-stage geographic sample was maintained, but participants were recruited in prenatal care provider offices. We describe our experience recruiting pregnant women this way in Wayne County, Michigan, a county where geographically eligible women attended 147 prenatal care settings, and comprised just 2% of total county pregnancies. Methods After screening for address eligibility in prenatal care offices, we used a three-part recruitment process: (1) providers obtained permission for us to contact eligible patients, (2) clinical research staff described the study to women in clinical settings, and (3) survey research staff visited the home to consent and interview eligible women. Results We screened 34065 addresses in 67 provider settings to find 215 eligible women. Providers obtained permission for research contact from 81.4% of eligible women, of whom 92.5% agreed to a home visit. All home-visited women consented, giving a net enrolment of 75%. From birth certificates, we estimate that 30% of eligible county pregnancies were enrolled, reaching 4050% in the final recruitment months. Conclusions We recruited a high fraction of pregnancies identified in a broad cross-section of provider offices. Nonetheless, because of time and resource constraints, we could enrol only a fraction of geographically eligible pregnancies. Our experience suggests that the probability sampling of pregnancies for research could be more efficiently achieved through sampling of providers rather than households.