Intracortical recording stability in human brain-computer interface users
Intracortical recording stability in human brain-computer interface users
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DOI：
10.1088/1741-2552/aab7a0
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发表时间：
2018-08-01
影响因子：
4
通讯作者：
Collinger, Jennifer L.
中科院分区：
文献类型：
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作者：
Downey, John E.;Schwed, Nathaniel;Collinger, Jennifer L.
目标。脑皮层内脑机接口（bci）正在被开发，以帮助运动障碍患者与周围的世界进行交流和互动。这项技术依赖于初级运动皮层的记录，这些记录可能每天都在变化。的方法。在这里，我们量化了两个长期脑机接口的受试者，从运动皮层记录同一神经元或神经元组的动作电位的时间长度。主要的结果。这些动作电位通过它们的细胞外波形来识别，可能在一天内发生变化，尽管其中一些已识别的单位可以连续数周甚至数月被识别。细胞外波形的特征使我们能够预测一个特定的单位是否更有可能在一段较长的时间内保持稳定。的意义。对单元稳定性和不稳定性的更好理解有助于运动脑机接口的发展，其目标是在记录人群发生变化的情况下保持高水平的表现。bci应该能够在没有技术人员干预的情况下操作数小时，甚至数天，从而为该技术的最终用户提供最大的利益。
Objective. Intracortical brain-computer interfaces (BCIs) are being developed to assist people with motor disabilities in communicating and interacting with the world around them. This technology relies on recordings from the primary motor cortex, which may vary from day to day. Approach. Here we quantify, in two long-term BCI subjects, the length of time that action potentials from the same neuron, or group of neurons, can be recorded from the motor cortex. Main results. These action potentials are identified by their extracellular waveforms and may change within a single day, although some of these identified units can be identified consistently for weeks and even months. Features of the extracellular waveforms allowed us to predict whether a specific unit was more or less likely to remain stable over a prolonged period. Significance. A greater understanding of unit stability and instability can aid the development of motor BCIs, where the goal is to maintain a high level of performance despite changes in the recorded population. BCIs should be able to be operated without technician intervention for hours, and hopefully days, to provide the most benefit to the end-users of this technology.