Defining hirsutism in Chinese women: a cross-sectional study
Defining hirsutism in Chinese women: a cross-sectional study
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中国女性多毛症的定义：一项横断面研究
DOI：
10.1016/j.fertnstert.2011.06.040
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发表时间：
2011-09-01
影响因子：
6.7
通讯作者：
Yang, Dongzi
中科院分区：
文献类型：
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作者：
Zhao, Xiaomiao;Ni, Renmin;Yang, Dongzi
目的：确定定义中国女性多毛症的规范截止分数，以及年龄、月经不调和多囊卵巢对其的影响。设计：基于人群的横断面研究。背景：对来自两个农村和两个城市地区的 16 个社区进行多阶段系统整群随机抽样。患者：2,988 名 20-45 岁女性的代表性样本 干预措施：受试者接受物理和超声评估。主要结果指标：使用改良的 Ferriman-Gallwey (mFG) 评分系统评估终毛生长。结果：10% 的受试者观察到 mFG 评分 >= 5，25% 的受试者评分 >= 2。聚类分析将 mFG 得分 5 确定为界值，定义总人口中男性模式的面部和身体末端毛发异常生长（即多毛症）； 20-25岁、26-30岁和>30岁女性的得分分别为6分、5分和4分。根据这些临界值，我国总人口中多毛症的患病率为 10.5%；随着年龄的增长而下降：20-25岁、26-30岁、31-35岁、36-40岁和41-45岁女性分别为14.4%、10.7%、7.9%、3.6%和1.5%。此外，多毛女性中痤疮、月经不调、多囊卵巢和黑棘皮病的发病率显着增加。结论：mFG 评分为 5 或更高表明中国南方人群中女性的毛发生长高于正常水平，该临界值随着年龄的增长而降低。 （Fertil Steril (R) 2011；96:792 6。(c) 2011 年，美国生殖医学会。）
Objective: To determine the normative cut-off score that defines hirsutism among Chinese women, and the effect of age, menstrual irregularities, and polycystic ovaries on the same.Design: Cross-sectional, population-based study.Setting: A multistage systematic cluster random sampling among 16 communities from two rural and two city regions.Patient(s): A representative sample of 2,988 women aged 20-45 years from the general population of Southern China.Intervention(s): Subjects underwent physical and ultrasound evaluations.Main Outcome Measure(s): Terminal hair growth was assessed using the modified Ferriman-Gallwey (mFG) scoring system.Result(s): An mFG score >= 5 was observed in 10% and a score of >= 2 in 25% of the subjects. Cluster analysis identified an mFG score of 5 as the cut-off value that defines abnormal terminal facial and body hair growth in a male pattern (i.e., hirsutism) in the total population; scores of 6, 5, and 4 for women aged 20-25, 26-30, and >30 years, respectively. Defined by these cut-off values, the prevalence of hirsutism in our total population was 10.5%; and decreased with increasing age: 14.4%, 10.7%, 7.9%, 3.6%, and 1.5%, respectively, in women aged 20-25, 26-30, 31-35, 36-40, and 41-45 years. Furthermore, the incidence of acne, menses irregularities, polycystic ovaries, and acanthosis nigricans were significantly increased among the hirsute women.Conclusion(s): An mFG score of 5 or greater indicates hair growth above the norm among women in the general Southern Chinese population, a cut-off value that decreases with increasing age. (Fertil Steril (R) 2011;96:792 6. (c) 2011 by American Society for Reproductive Medicine.)