Dietary intake of vitamin D and cognition in older women A large population-based study
Dietary intake of vitamin D and cognition in older women A large population-based study
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DOI：
10.1212/wnl.0b013e3181fd6352
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发表时间：
2010-11-16
期刊：
影响因子：
9.9
通讯作者：
Beauchet, O.
中科院分区：
文献类型：
--
作者：
Annweiler, C.;Schott, A. M.;Beauchet, O.
背景：血清维生素D浓度与老年人的整体认知功能相关。摄入维生素D对治疗或预防认知障碍的益处仍然未知。这项横断面研究的目的是确定每周膳食摄入维生素D是否与老年人的整体认知能力有关。方法：一共5个，596名社区妇女（平均年龄80.5 +/- 0.1岁），未服用骨质疏松症流行病学（EPIDOS）提供的维生素D药物补充剂根据基线每周维生素D饮食摄入量（不足= 35 μ g/周）将研究分为2组。每周的维生素D饮食摄入量通过自我管理的食物频率问卷进行估计。认知功能障碍的定义为Pfeiffer简明精神状态问卷（SPMSQ）评分
Background: Serum vitamin D concentrations are associated with global cognitive function among older adults. The benefits of vitamin D intake to treat or prevent cognitive impairment remain unknown. The objective of this cross-sectional study was to determine whether weekly dietary intake of vitamin D could be associated with global cognitive performance among older adults.Methods: A total of 5,596 community-dwelling women (mean age 80.5 +/- 0.1 years) free of vitamin D drug supplements from the Epidemiologie de l'Osteoporose (EPIDOS) study were divided into 2 groups according to baseline weekly vitamin D dietary intake (either inadequate = 35 mu g/wk). Weekly vitamin D dietary intakes were estimated from a self-administered food frequency questionnaire. Cognitive impairment was defined as a Pfeiffer Short Portable Mental State Questionnaire (SPMSQ) score