CALCIUM UPTAKE AND RELEASE BY DIVIDING SEA-URCHIN EGGS
CALCIUM UPTAKE AND RELEASE BY DIVIDING SEA-URCHIN EGGS
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DOI：
10.1016/0014-4827(72)90525-3
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发表时间：
1972-01-01
影响因子：
3.7
通讯作者：
TIMOURIAN, H
中科院分区：
文献类型：
--
作者：
CLOTHIER, G;TIMOURIAN, H
在卵裂早期，海胆卵在海水中提供45ca时，表现出明显的活性高峰，代表了45ca的吸收和释放。在每个分裂周期中，分别观察到前期、中期和50%卵裂的三个明显的峰。当外源40ca供应时，细胞内的45ca似乎是自由的，并且能够外排。讨论了观察到的45ca峰与(a)卵细胞浆粘度变化的关系；(b)有丝分裂器的形成；(c)局部膜收缩和舒张；(d)膜透性的循环变化；(e)辅因子要求。
During early cleavage stages the sea urchin egg, when supplied with45Ca in the sea water shows distinct peaks of activity representing uptake and release of the45Ca. Three distinct peaks corresponding with prophase, metaphase and 50% cleavage, were observed during each division cycle. The45Ca inside the cells appeared to be free and capable of efflux when exogenous40Ca was supplied. The observed45Ca peaks were discussed in relation to (a) viscosity changes in egg cytoplasm; (b) formation of the mitotic apparatus; (c) regional membrane contraction and relaxation; (d) cyclic changes in membrane permeability; (e) cofactor requirements.