Energetics of stress: linking plasma cortisol levels to metabolic rate in mammals
Energetics of stress: linking plasma cortisol levels to metabolic rate in mammals
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DOI：
10.1098/rsbl.2015.0867
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发表时间：
2016-01-01
期刊：
影响因子：
3.3
通讯作者：
Gillooly, James F.
中科院分区：
文献类型：
--
作者：
Haase, Catherine G.;Long, Andrea K.;Gillooly, James F.
生理压力可能会对生物体的表现产生短期的好处，但也会对健康或寿命产生长期的代价。然而，我们缺乏对存在于物种内和物种间的应激激素水平（即糖皮质激素）变化的了解。在这里，我们提出了比较分析，链接在大多数哺乳动物的主要应激激素（即皮质醇）的代谢率。我们发现，血浆皮质醇的基线浓度随皮质醇占主导地位的哺乳动物的特定质量代谢率而变化，基线和升高的浓度都随体重而变化。结果定量联系的生理压力的经典措施，整个有机体能量学，提供了一个出发点，哺乳动物之间的压力水平的跨物种比较。
Physiological stress may result in short-term benefits to organismal performance, but also long-term costs to health or longevity. Yet, we lack an understanding of the variation in stress hormone levels (i.e. glucocorticoids) that exist within and across species. Here, we present comparative analyses that link the primary stress hormone in most mammals (i.e. cortisol) to metabolic rate. We show that baseline concentrations of plasma cortisol vary with mass-specific metabolic rate among cortisol-dominant mammals, and both baseline and elevated concentrations scale predictably with body mass. The results quantitatively link a classical measure of physiological stress to whole-organism energetics, providing a point of departure for cross-species comparisons of stress levels among mammals.