Human glucose-6-phosphate dehydrogenase variants.
Human glucose-6-phosphate dehydrogenase variants.
复制标题
DOI：
--
复制
发表时间：
1971
影响因子：
11.1
通讯作者：
A. Yoshida;E. Beutler;A. Motulsky
中科院分区：
文献类型：
--
作者：
A. Yoshida;E. Beutler;A. Motulsky
已经描述了如此多的葡萄糖-6-磷酸脱氢酶（G6 PD）变体，以至于很难确定新发现的变体是否与其他变体不同。这一困难可以通过进行一些物理化学试验并将结果与已知变体的已报告结果进行比较来部分克服。本次交流的目的是提供一个最新的表格，总结了目前可用的G6 PD变体数据。为了方便起见，根据它们在红细胞中的活性及其相关的临床表现，在附表中描述的变体在某种程度上被任意地分为五类：
So many glucose-6-phosphate dehydrogenase (G6PD) variants have been described that it has become very difficult to determine whether or not a newly discovered variant is distinct from any other. This difficulty can be partially overcome by performing a number of physicochemical tests and comparing the results with those already reported for the known variants. The purpose of this communication is to provide an up-to-date table summarizing the currently available data on G6PD variants. For purposes of convenience, the variants described in the accompanying table are somewhat arbitrarily divided into five classes, in accordance with their activity in red cells and their associated clinical manifestations: