Inadequate adherence to antiretroviral treatment and prevention in hospital and community sites in Burkina Faso and Mali: a study by the ATARAO group

Inadequate adherence to antiretroviral treatment and prevention in hospital and community sites in Burkina Faso and Mali: a study by the ATARAO group
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DOI:
10.1258/095646207782212243
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发表时间:
2007-11-01
影响因子:
1.4
通讯作者:
Rashed, S.
Rashed, S.
中科院分区:
医学4区
文献类型:
--
作者:
Aboubacrine, S. Ag;Niamba, P.;Rashed, S.

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我们的目标是确定流行率,并确定影响巴马科和瓦加杜古患者坚持抗逆转录病毒治疗(ART)的因素。在接受ART的94名男性和176名女性中进行了一项横断面研究。通过问卷调查和图表审查收集数据。进行Logistic回归以分离依从性的决定因素。总体而言,58%的患者依从,但依从性水平因国家和治疗中心而异。社会人口因素与依从性无关。然而,社会特征,如在瓦加杜古有孩子,或在巴马科是家庭主妇,明年不打算有孩子,与坚持有关。在这两个国家,抗逆转录病毒治疗的时间与依从性呈负相关,巴马科的依从性下降较晚。依从性水平不足,特别是在经验丰富的患者中。进一步的依从性研究和监测使用纵向设计是必要的,以评估依从性随治疗时间的下降程度。
Our objective was to determine the prevalence and identify the factors that influence antiretroviral therapy (ART) adherence among patients in Bamako and Ouagadougou. A cross-sectional study was conducted among 94 men and 176 women receiving ART Data were collected through questionnaires and chart reviews. Logistic regressions were performed to isolate determinants of adherence. Overall, 58% of the patients were adherent, but there were differences in the levels of adherence according to country and treatment site. Sociodemographic factors were not associated with adherence. However, social characteristics such as having children, in Ouagadougou, or being a housewife and not planning to have a child in the next year, in Bamako were associated with adherence. Time on ART was negatively associated with adherence in both countries with decline occurring later in Bamako. Levels of adherence are inadequate particularly among more experienced patients. Further adherence research and monitoring using longitudinal designs are warranted to assess the extent to which adherence is declining with time on treatment.