HISTORICAL NOTE ON IODINE SULFURIC ACID REACTION OF AMYLOID
HISTORICAL NOTE ON IODINE SULFURIC ACID REACTION OF AMYLOID
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DOI：
10.1007/bf00495677
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发表时间：
1976-01-01
期刊：
影响因子：
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通讯作者：
ATERMAN, K
中科院分区：
文献类型：
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作者：
ATERMAN, K
介绍了碘-硫酸反应制备淀粉样蛋白的历史发展。该反应可以追溯到1814年，当时Colin和Gaultier de Claubry以及Stromeyer独立地介绍了淀粉的I2反应。Gmelin在1829年将酸化I2反应的一种变体用于印刷纸，1838年Schleiden在植物上使用I2-硫酸试验来证明植物材料转化为淀粉。Payen（1839）定义了纤维素，I2-硫酸反应成为植物学家用来证明这种植物成分的标准程序。1853年，Virchow使用Harting（1847）的方法证明了Purkyne氏淀粉体对该试验的反应，假设它们可能是纤维素衍生物，并将其应用于蜡质脾脏中似乎类似的小体。淀粉样变性的第一个组织化学反应因此被引入病理学，并继续对淀粉样蛋白的研究产生重要影响。
The historical development of the I2-sulfuric acid reaction for amyloid is described. The reaction dates back to 1814 when Colin and Gaultier de Claubry, and independently Stromeyer, introduced the I2 reaction for starch. A variant of the acidified I2 reaction was used for printing paper by Gmelin in 1829, and in 1838 Schleiden used the I2-sulfuric acid test on plants to demonstrate a transformation of the plant material into starch. Payen (1839) defined cellulose, and the I2-sulfuric acid reaction became a standard procedure used by botanists to demonstrate this plant component. In 1853 Virchow used Harting''s (1847) procedure to demonstrate the reaction of Purkyne''s corpora amylacea to this test, on the assumption that they might be cellulose derivatives, and applied it to what appeared to be similar corpuscles in a waxy spleen. The 1st histochemical reaction for amyloidosis had thus been introduced into pathology, and continued to exert an important influence on amyloid research.