An appraisal of whole-room indirect calorimeters and a metabolic cart for measuring resting and active metabolic rates
An appraisal of whole-room indirect calorimeters and a metabolic cart for measuring resting and active metabolic rates
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DOI：
10.1038/s41598-020-71001-1
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发表时间：
2020-08-31
影响因子：
4.6
通讯作者：
Celi, Francesco S.
中科院分区：
文献类型：
--
作者：
Chen, Shanshan;Scott, Cory;Celi, Francesco S.
传统上，全室间接热量计（WRIC）用于实时静息代谢率（RMR）测量，而短间隔运动期间的代谢率（MR）通常由代谢车（MC）测量。本研究的目的是通过比较WRIC和MC的表现，探讨将短间隔运动纳入WRIC研究方案的可行性。我们评估了40分钟的RMR的15名受试者与2天的重复和10-15分钟的活动MR（AMR）的14名受试者在三个强度，使用一个大的WRIC，一个小的WRIC，和MC。我们使用方差分量分析评估了工具之间的偏差和量化的变异来源。所有三种仪器均显示RMR（最大偏倚=0.07 kcal/min）和AMR评估（最大偏倚=0.53 kcal/min）具有良好的一致性。此外，大多数变异性是受试者间和强度间变异，而仪器类型仅对RMR（2%）和AMR（0.2%）数据的总变异性有少量贡献。结论：仪器之间良好的重复性表明它们可以在设计良好的研究中互换使用。总的来说，WRIC可以作为一种准确和通用的MR评估方法，能够将RMR和短间隔AMR评估整合到单一方案中。
Whole-room indirect calorimeters (WRICs) have traditionally been used for real-time resting metabolic rate (RMR) measurements, while metabolic rate (MR) during short-interval exercises has commonly been measured by metabolic carts (MCs). This study aims to investigate the feasibility of incorporating short-interval exercises into WRIC study protocols by comparing the performance of WRICs and an MC. We assessed the 40-min RMR of 15 subjects with 2-day repeats and the 10-15 min activity MR (AMR) of 14 subjects at three intensities, using a large WRIC, a small WRIC, and an MC. We evaluated the biases between the instruments and quantified sources of variation using variance component analysis. All three instruments showed good agreement for both RMR (maximum bias=0.07 kcal/min) and AMR assessment (maximum bias=0.53 kcal/min). Moreover, the majority of the variability was between-subject and between-intensity variation, whereas the types of instrument contributed only a small amount to total variation in RMR (2%) and AMR (0.2%) data. In Conclusion, the good reproducibility among the instruments indicates that they may be used interchangeably in well-designed studies. Overall, WRICs can serve as an accurate and versatile means of assessing MR, capable of integrating RMR and short-interval AMR assessments into a single protocol.