Effects of dietary supplementation with flax during prepuberty on fatty acid profile, mammogenesis, and bone resorption in gilts
Effects of dietary supplementation with flax during prepuberty on fatty acid profile, mammogenesis, and bone resorption in gilts
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DOI：
10.2527/jas.2007-0022
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发表时间：
2007-07-01
影响因子：
3.3
通讯作者：
Capuco, A. V.
中科院分区：
文献类型：
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作者：
Farmer, C.;Petit, H. V.;Capuco, A. V.
在后备母猪中研究了日粮亚麻对乳腺青春期前发育和骨吸收的可能作用。57头后备母猪从88日龄开始饲喂4种日粮中的1种，直至屠宰（212±1日龄）。日粮分别为：不含亚麻的对照日粮（n = 14）；添加10%亚麻籽日粮（n = 13）；添加6.5%亚麻籽粕日粮（n = 15）；添加3.5%亚麻籽油日粮（n = 15）。所有日粮含氮量和热量均相同。在第78天和第210天采集颈静脉血样，以确定脂肪酸组成，并测定催乳素、雌二醇和I型胶原交联N -端肽的浓度。屠宰时，切除乳腺，解剖实质组织和实质外组织，并测定实质组织的成分（蛋白质、脂肪、干物质和DNA）。对乳腺实质进行了组织化学分析，并评估了实质外组织的脂肪酸组成。日粮中的亚麻使（P < 0.05）血浆中α -亚麻酸和二十碳五烯酸浓度升高，而使花生四烯酸浓度降低。亚麻籽和亚麻籽油日粮使（P < 0.05）血浆中n - 3多不饱和脂肪酸与n - 6多不饱和脂肪酸的比值升高。亚麻籽和亚麻籽油日粮使（P < 0.05）血浆中催乳素浓度升高，而对雌二醇浓度无影响（P > 0.05）。亚麻籽和亚麻籽油日粮使（P < 0.05）乳腺实质组织中蛋白质和DNA含量升高，而对脂肪和干物质含量无影响（P > 0.05）。亚麻籽和亚麻籽油日粮使（P < 0.05）乳腺实质组织中腺泡数量增加，腺泡大小无变化（P > 0.05）。亚麻籽和亚麻籽油日粮使（P < 0.05）实质外组织中α -亚麻酸和二十碳五烯酸浓度升高，而使花生四烯酸浓度降低。亚麻籽和亚麻籽油日粮使（P < 0.05）实质外组织中n - 3多不饱和脂肪酸与n - 6多不饱和脂肪酸的比值升高。亚麻籽和亚麻籽油日粮对骨吸收无影响（P > 0.05）。总之，日粮中的亚麻籽和亚麻籽油可改变乳腺发育，但对骨吸收无影响。
The possible role of dietary flax on prepubertal development of mammary glands and bone resorption was investigated in gilts. Fifty-seven gilts were fed 1 of 4 diets from 88 d of age until slaughter (d 212 +/- 1). Diets were control without flax (n = 14); 10% flaxseed supplementation (n = 13); 6.5% flaxseed meal supplementation (n = 15); and 3.5% flaxseed oil supplementation (n = 15). All diets were isonitrogenous and isocaloric. Jugular blood samples were obtained on d 78 and 210 to establish the fatty acid profile and to determine the concentrations of prolactin, estradiol, and cross-linked N-telopeptides of type I collagen. At slaughter, the mammary glands were excised, parenchymal and extraparenchymal tissues were dissected, and the composition of the parenchymal tissue (protein, fat, DM, and DNA) was determined. Histochemical analyses of the mammary parenchyma were performed, and fatty acid profiles in the extraparenchymal tissue were evaluated. Dietary flax increased (P