Premorbid weight, body mass, and varsity athletics in ALS
Premorbid weight, body mass, and varsity athletics in ALS
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DOI：
10.1212/wnl.59.5.773
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发表时间：
2002-09-10
期刊：
影响因子：
9.9
通讯作者：
Rowland, LP
中科院分区：
文献类型：
--
作者：
Scarmeas, N;Shih, T;Rowland, LP
几名著名运动员都曾受到肌萎缩侧索硬化症的影响，一些流行病学研究表明，剧烈的体力活动(繁重的劳动或田径运动)是该病的危险因素。在对279名运动神经元病患者和152名其他神经系统疾病患者进行的病例对照研究中，作者发现，运动神经元病患者比对照组更有可能报告自己一直很苗条，或者他们曾是校队运动员。对于苗条，优势比(OR)为2.21；95%可信区间(CI)为1.40至3.47。对于大学田径队，OR为1.70；CI为1.04至2.76。
Several famous athletes have been affected by ALS, and some epidemiologic studies have indicated that vigorous physical activity (heavy labor or athletics) is a risk factor for the disease. In a case-control study of 279 patients with motor neuron diseases and 152 with other neurologic diseases, the authors found that subjects with motor neuron diseases were more likely than controls to report they had always been slim or they had been varsity athletes. For slimness, the odds ratio (OR) was 2.21; 95% CI, 1.40 to 3.47. For varsity athletics, the OR was 1.70; CI, 1.04 to 2.76.