Secondary leukemia after treatment with paclitaxel and carboplatin in a patient with recurrent ovarian cancer
Secondary leukemia after treatment with paclitaxel and carboplatin in a patient with recurrent ovarian cancer
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复发性卵巢癌患者接受紫杉醇和卡铂治疗后继发性白血病
DOI:
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发表时间:
2005
期刊:
影响因子:
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通讯作者:
J. Kavanagh
中科院分区:
文献类型:
--
作者:
H. See;D. Thomas;C. Bueso;J. Kavanagh
The occurrence of myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML) has been reported after treatment with cytotoxic alkylating agent–based chemotherapy for solid tumors. We report a patient with metastatic ovarian carcinoma treated with carboplatin and paclitaxel, who developed secondary acute erythroid leukemia. The overall survival of patients with stage III and IV ovarian cancer has increased in the past decade. Monitoring of the long-term outcome of paclitaxel- and platinum-based regimens is warranted, particularly with regard to monitoring the development of secondary MDS and/or AML. The incidence and outcome of secondary leukemia in the setting of active ovarian carcinoma is reviewed.
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影响因子:
20.3
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