Trace eyeblink classical conditioning in the monkey: a nonsurgical method and behavioral analysis.
Trace eyeblink classical conditioning in the monkey: a nonsurgical method and behavioral analysis.
复制标题
追踪猴子的眨眼经典条件反射：非手术方法和行为分析。
DOI：
10.1037//0735-7044.112.5.1062
复制
发表时间：
1998
影响因子：
1.9
通讯作者：
Zola,S
中科院分区：
文献类型：
--
作者：
Clark,RE;Zola,S
经典的眨眼条件反射已被广泛用于研究兔子和人类的联想学习和记忆的神经生物学。在过去的几年里，新的发展已经重新引起了人们对研究猴子经典条件反射的可能性的兴趣。具体来说，现在已知的是，条件反射受损可以在具有各种神经问题的人类中观察到，包括健忘症，因此现在对人类眨眼条件反射的神经生物学有相当大的兴趣。涉及猴子的研究可以产生解剖学上定义的神经结构的离散病变，有可能提供可能无法从人类工作中获得的信息。在这里，作者提出了一个简单的，非手术的方法，经典条件反射的眨眼反应在猴子和报告的行为结果，使用跟踪条件反射范式，是敏感的海马损伤在兔子和人类。这种方法是可靠和有效的记录眨眼，并表明，强大的眨眼经典条件反射可以很容易地建立在猴子。（PsycINFO数据库记录（c）2016阿帕，保留所有权利）
Classical eyeblink conditioning has been used extensively to study the neurobiology of associative learning and memory in rabbits and in humans. During the last several years, new developments have renewed interest in the possibility of studying classical conditioning in monkeys. Specifically, it is now known that impaired conditioning can be observed in humans with various neurologic problems, including amnesia, and thus there is now considerable interest in the neurobiology of human eyeblink conditioning. Research involving monkeys, in which discrete lesions of anatomically defined neural structures can be produced, has the potential to provide information that might not be readily available from work in humans. Here, the authors present a simple, nonsurgical method for classically conditioning the eyeblink response in monkeys and report behavioral results using a trace conditioning paradigm that is sensitive to hippocampal damage in both rabbits and humans. This method is reliable and effective for recording eyeblinks and shows that robust eyeblink classical conditioning can be readily established in the monkey.(PsycINFO Database Record (c) 2016 APA, all rights reserved)