Paper-based microfluidics: Simplified fabrication and assay methods

Paper-based microfluidics: Simplified fabrication and assay methods
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DOI:
10.1016/j.snb.2021.129681
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发表时间:
2021-03-05
影响因子:
8.4
通讯作者:
Awan, Fazli Rabbi
Awan, Fazli Rabbi
中科院分区:
化学1区
文献类型:
--
作者:
Nishat, Sumaira;Jafry, Ali Turab;Awan, Fazli Rabbi

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纸基微流体是微流体的分支,涉及由纸或其他多孔膜制成的装置,其通过毛细作用芯吸流体。纸基微流体装置具有优于常规微流体装置的若干优点,包括更简单的制造、更低的成本、更容易的处置以及在没有泵或其它支持设备的情况下操作的能力。纸基微流体设备最常见的应用是开发即时护理(POC)诊断设备,这可以消除对昂贵且耗时的实验室分析程序的需求。本文综述了目前纸基微流控器件的制作方法,这些设备的应用实例,讨论了它们目前的局限性,并展望了它们的未来。
Paper-based microfluidics is the branch of microfluidics involving devices made out of paper, or other porous membranes, that wick fluids by capillary action. Paper-based microfluidic devices have several advantages over conventional microfluidic devices including simpler fabrication, lower cost, easier disposal, and the ability to operate without pumps or other supporting equipment. The most common application of paper-based microfluidic devices is in the development of point-of-care (POC) diagnostic devices, which could eliminate the need for costly and time-consuming laboratory-based analytical procedures. This review provides an overview of current methods of fabricating paper-based microfluidic devices, examples of applications of these devices, a discussion of their current limitations, and an outlook on their future.