On the evolution of bilaterality
On the evolution of bilaterality
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DOI：
10.1242/dev.141507
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发表时间：
2017-10-01
期刊：
影响因子：
4.6
通讯作者：
Technau, Ulrich
中科院分区：
文献类型：
--
作者：
Genikhovich, Grigory;Technau, Ulrich
双面性--拥有两个相互垂直的身体轴线--是所有双边动物的命名特征。这些体轴是在早期胚胎发育期间建立的，并作为一个三维坐标系，为细胞、组织、器官和附件的发育提供关键的空间线索。双面性的出现是一个重大的进化转变，因为它允许动物进化出更复杂的身体规划。因此，双边是如何进化的，它是一次还是几次独立进化，是进化发展生物学的一个基本问题。来自非双边动物的最新发现，特别是来自Cnidaria的发现，为双边进化的起源提供了新的线索。在这里，我们比较了径向和两侧对称的线虫和双边线虫对体轴的分子控制，确定了双向线虫共有的最小特征集，并评估了双边特性在进化过程中是出现一次还是不止一次。
Bilaterality - the possession of two orthogonal body axes - is the name-giving trait of all bilaterian animals. These body axes are established during early embryogenesis and serve as a three-dimensional coordinate system that provides crucial spatial cues for developing cells, tissues, organs and appendages. The emergence of bilaterality was a major evolutionary transition, as it allowed animals to evolve more complex body plans. Therefore, how bilaterality evolved and whether it evolved once or several times independently is a fundamental issue in evolutionary developmental biology. Recent findings from non-bilaterian animals, in particular from Cnidaria, the sister group to Bilateria, have shed new light into the evolutionary origin of bilaterality. Here, we compare the molecular control of body axes in radially and bilaterally symmetric cnidarians and bilaterians, identify the minimal set of traits common for Bilateria, and evaluate whether bilaterality arose once or more than once during evolution.