INTERRATER RELIABILITY IN ASSESSING FUNCTIONAL-SYSTEMS AND DISABILITY ON THE KURTZKE SCALE IN MULTIPLE-SCLEROSIS
INTERRATER RELIABILITY IN ASSESSING FUNCTIONAL-SYSTEMS AND DISABILITY ON THE KURTZKE SCALE IN MULTIPLE-SCLEROSIS
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DOI：
10.1001/archneur.1988.00520310052017
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发表时间：
1988-07-01
影响因子：
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通讯作者：
AMADUCCI, L
中科院分区：
文献类型：
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作者：
AMATO, MP;FRATIGLIONI, L;AMADUCCI, L
在使用定量量表评估神经功能缺陷方面，审查员之间的一致意见对于多发性硬化症合作研究的临床数据的可靠性至关重要。在这项研究中，四名神经学家分成六对，检查了24名明确患有多发性硬化症的患者，并根据Kurtzke量表评估了每个功能系统和残疾。用。kappa表示。指数，观察者之间的一致性相当低，从30%到50%不等。感觉和心理功能是变化最大的。.kappa。指数达到85%以上，当评分者的差异不超过1分时，就被视为同意。量表上最多两个单位的点差似乎是临床变化的可靠指标。此外，这些结果指出了在多中心调查中对评分员和观察者间变异性进行周期性控制的特定培训计划的必要性。
Interexaminer agreement in the use of quantitative scales for the evaluation of neurological deficits is essential to the reliability of clinical data from cooperative studies on multiple sclerosis. In this study, four neurologists, arranged into six pairs, examined 24 patients with definite multiple sclerosis and assessed each functional system and disability on the Kurtzke scale. As expressed by the .kappa. index, interobserver agreement was rather low, ranging from 30% to 50%. Sensory and mental functions turned out to be the most variable. The .kappa. indexes reached values above 85%, when raters who differed by no more than one point were considered as agreeing. A point difference on the scale of, at most, two units seemed to be a reliable index of clinical change. Moreoer, these results pointed to the necessity for a specific training program for raters and for periodic control of interobserver variability in multi-center surveys.