EnsurePlus as an Alternative to the Standardized Egg Gastric-Emptying Meal
EnsurePlus as an Alternative to the Standardized Egg Gastric-Emptying Meal
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DOI：
10.1097/rlu.0000000000002553
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发表时间：
2019-06-01
影响因子：
10.6
通讯作者：
Ziessman, Harvey A.
中科院分区：
文献类型：
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作者：
Solnes, Lilja B.;Sheikhbahaei, Sara;Ziessman, Harvey A.
目的 本研究的目的是确定健康受试者中 EnsurePlus 的正常胃排空值，并确定它是否是推荐的标准化 Tc-99m-硫胶体蛋粉的可接受替代品。方法 21 名健康受试者使用 In-111-DTPA EnsurePlus 进行胃排空闪烁扫描。餐后 1、2、3 和 4 小时确定正常胃排空值。将胃排空结果与另一组摄入标准化鸡蛋餐的正常受试者（n = 18）进行比较。结果 EnsurePlus 胃潴留百分比平均（95% 参考上限）如下：1 小时时为 69.9% (87.1%)，2 小时时为 35.1% (64.3%)，3 小时时为 13.5% (23.2%)，4 小时时为 8.9% (13.5%)。与鸡蛋餐相比，EnsurePlus 的胃排空存在时间相关的差异。在第一和第二小时，EnsurePlus 和蛋粉之间的保留百分比没有差异（1 小时时 P = 0.92，2 小时时 P = 0.05）。然而，在餐后 3 小时和 4 小时，EnsurePlus 的平均胃滞留百分比显着高于鸡蛋餐 (P < 0.001)。结论 EnsurePlus 是标准化蛋粉的良好且可接受的替代品。
Objectives The purpose of this study was to establish normal gastric-emptying values for EnsurePlus in healthy subjects and to determine whether it is an acceptable alternative to the recommended standardized Tc-99m-sulfur colloid egg meal. Methods Twenty-one healthy subjects underwent gastric-emptying scintigraphy with In-111-DTPA EnsurePlus. Normal gastric emptying values were established for 1, 2, 3, and 4 hours after meal ingestion. The gastric-emptying results were compared with another group of normal subjects (n = 18) who ingested the standardized egg meal. Results The mean (95% upper reference limit) percentages for gastric retention for EnsurePlus were as follows: 69.9% (87.1%) at 1 hour, 35.1% (64.3%) at 2 hours, 13.5% (23.2%) at 3, and 8.9% (13.5%) at 4 hours. There were time-related differences in the gastric emptying of the EnsurePlus compared with the egg meal. In the first and second hours, there were no difference between EnsurePlus and the egg meal in terms of percentage retention (P = 0.92 at 1 hour, P = 0.05 at 2 hours). However, at 3 and 4 hours after meal ingestion, the mean percentage gastric retention of the EnsurePlus was significantly higher than the egg meal (P < 0.001). Conclusion EnsurePlus is a good and acceptable alternative to the standardized egg meal.