Four-year observation of predictability and stability of small incision lenticule extraction.
Four-year observation of predictability and stability of small incision lenticule extraction.
复制标题
小切口微透镜取出的可预测性和稳定性的四年观察
DOI：
10.1186/s12886-016-0331-0
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发表时间：
2016-08-30
影响因子：
2
通讯作者：
Zhou X
中科院分区：
文献类型：
--
作者：
Han T;Zheng K;Chen Y;Gao Y;He L;Zhou X
目的探讨小切口屈光矫正术（small incision crystalleextraction，SMILE）治疗中高度近视的远期疗效、波前像差及生活质量。测量包括未矫正远视力（UDVA），矫正远视力（CDVA），显性屈光，波前像差，和quality of life.ResultsAt 4 years postoperative，UDVA优于或等于20/20在92%的眼睛。疗效指数为1.07 ± 0.16。89%的眼睛在预期屈光目标的± 0.5 D范围内。没有眼睛失去任何Snellen线。安全指数为1.16 ± 0.14。术后1、3、6个月和1、2、4年随访时SE无显著性变化（P> 0.05，Scheffe检验）。术后高阶像差、彗差、球面像差和高阶散光增加，术后1个月、6个月和4年随访（37眼），像差无明显变化。手术组的生活质量总分（45.71 ± 2.61）分明显高于眼镜组（39.96 ± 3.56，P < 0.001）。
BackgroundTo investigate long-term refractive outcomes, wavefront aberrations and quality of life after small incision lenticule extraction (SMILE) for moderate to high myopia.MethodsA total of 26 patients (47 eyes) with preoperative mean spherical equivalent (SE) of -6.30 ± 1.47 diopters (D) who underwent SMILE were recruited. The measurements included uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), manifest refraction, wavefront aberrations, and quality of life.ResultsAt 4 years postoperatively, UDVA was better than or equal to 20/20 in 92 % of eyes. The efficacy index was 1.07 ± 0.16. 89 % of eyes were within ± 0.5 D of the intended refractive target. No eye lost any Snellen lines. The safety index was 1.16 ± 0.14. No significant changes of SE occurred among postoperative follow-ups at months 1, 3, 6 and years 1, 2, 4 (P> 0.05, Scheffe test). Higher-order aberrations, coma, spherical aberration and higher-order astigmatism increased postoperatively, and no significant changes of aberrations were detected among the 1-month, 6-month or 4-year follow-ups postoperatively (37 eyes). Compared to the spectacles group, the surgery group showed a significantly higher total score on quality of life (45.71 ± 2.61 vs 39.96 ± 3.56,P< 0.001).ConclusionsSMILE provides a predictable and stable correction of moderate to high myopia as documented by long-term follow-up.