Changes in NK and NKT cells in mesenteric lymph nodes after a Schistosoma japonicum infection
Changes in NK and NKT cells in mesenteric lymph nodes after a Schistosoma japonicum infection
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DOI：
10.1007/s00436-013-3732-5
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发表时间：
2014-03-01
影响因子：
2
通讯作者：
Huang, Jun
中科院分区：
文献类型：
--
作者：
Luo, Xueping;Xie, Hongyan;Huang, Jun
The mesenteric lymph node (MLN) is the main draining lymph node in mouse enterocoelia, which contains many types of immune cells. Among these cells, natural killer (NK) and natural killer T (NKT) cells belong to innate lymphoid cells (ILCs), which have potent activities for controlling a variety of pathogenic infections. In this study, C57BL/6 mice were infected with Schistosoma japonicum for 5-7 weeks. Lymphocytes were isolated from the MLN to detect changes in the phenotype and function of NK and NKT cells using a fluorescence activating cell sorter (FACS). These results demonstrated that a S. japonicum infection could significantly increase the percentage of NK cells in the mouse MLN, (P
