Efficient and divergent synthesis of cyclophosphamide analogues from 2-arylamino-3-acetyl-5,6-dihydro-4H-pyrans.
Efficient and divergent synthesis of cyclophosphamide analogues from 2-arylamino-3-acetyl-5,6-dihydro-4H-pyrans.
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DOI：
10.1039/b815416c
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发表时间：
2008-11
影响因子：
4.9
通讯作者：
Dexuan Xiang;Peng-mian Huang;Kewei Wang;Guang-Pei Zhou;Yongjiu Liang;D. Dong
中科院分区：
文献类型：
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作者：
Dexuan Xiang;Peng-mian Huang;Kewei Wang;Guang-Pei Zhou;Yongjiu Liang;D. Dong
以2-芳氨基-3-乙酰基-5，6-二氢-4H-吡喃为原料，一锅法合成了取代的环磷酰胺氯化物及其类似物。
A facile and efficient one-pot synthesis of substituted cyclophosphamidic chlorides and their analogues has been developed from readily available enaminones, 2-arylamino-3-acetyl-5,6-dihydro-4H-pyrans.