Pediatric abdominal masses: diagnostic accuracy of diffusion weighted MRI

Pediatric abdominal masses: diagnostic accuracy of diffusion weighted MRI
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DOI:
10.1016/j.mri.2010.02.010
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发表时间:
2010-06-01
影响因子:
2.5
通讯作者:
Tayfun, Cem
Tayfun, Cem
中科院分区:
医学4区
文献类型:
--
作者:
Kocaoglu, Murat;Bulakbasi, Nail;Tayfun, Cem

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目的:回顾性鉴定儿童腹部肿块病变的表观扩散系数 (ADC) 值,以确定测量的病变 ADC 和扩散加权 (DW) 图像上的信号强度是否可以区分良性和恶性肿块病变​​。 材料和方法:这项回顾性研究获得了机构审查委员会的批准。本研究纳入经 DW 磁共振成像 (MRI) 检查的腹部肿块病变儿童。 DW MR 图像是通过在 1.5-T MR 扫描仪上使用非屏气单次自旋回波序列在轴向平面上获得的。计算每个病变的 ADC。 ADC值与Mann-Whitney U检验进行比较。进行受试者工作特征曲线分析以确定 ADC 的截止值。将b800图像和ADC图图像的视觉评估结果与卡方检验进行比较。结果:26例患者(女15例,男11例,2天至17年,平均6.9岁)31个腹部肿块病灶(良性16个,恶性15个)接受MRI检查。良性病变的 ADC 值显着高于恶性病变(P
Purpose: To retrospectively identify apparent diffusion coefficient (ADC) values of pediatric abdominal mass lesions, to determine whether measured ADC of the lesions and signal intensity on diffusion-weighted (DW) images allow discrimination between benign and malignant mass lesions.Materials and Methods: Approval for this retrospective study was obtained from the institutional review board. Children with abdominal mass lesions, who were examined by DW magnetic resonance imaging (MRI) were included in this study. DW MR images were obtained in the axial plane by using a non breath-hold single-shot spin-echo sequence on a 1.5-T MR scanner. ADCs were calculated for each lesion. ADC values were compared with Mann-Whitney U test. Receiver operating characteristic curve analysis was performed to determine cut-off values for ADC. The results of visual assessment on b800 images and ADC map images were compared with chi-square test.Results: Thirty-one abdominal mass lesions (16 benign, 15 malignant) in 26 patients (15 girls, 11 boys, ranging from 2 days to 17 years with 6.9 years mean) underwent MRI. Benign lesions had significantly higher ADC values than malignant ones (P