COMPUTERIZED EEG IN SCHIZOPHRENIC-PATIENTS

COMPUTERIZED EEG IN SCHIZOPHRENIC-PATIENTS
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DOI:
10.1016/0006-3223(90)90482-h
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发表时间:
1990-09-15
影响因子:
10.6
通讯作者:
MATSUSHITA, M
MATSUSHITA, M
中科院分区:
医学1区
文献类型:
--
作者:
MIYAUCHI, T;TANAKA, K;MATSUSHITA, M

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我们对30名未经治疗的右利手患者进行了脑电图(EEG)研究(27.3 ± 0.01)。10.0年; hebephrenic,16;偏执狂,12岁;残差,2)符合ICD-9精神分裂症标准,并将其与性别和年龄匹配的对照组进行比较,使用6个EEG频带的功率百分比计算为总功率的分数。t-统计显著性概率图(t-SPM)显示,与正常对照组相比,精神分裂症患者顶枕区的慢活动(δ、θ和α 1)较多,枕区的快活动(β 1)较多。相比之下,α 2活性在枕叶区域急剧下降,这种下降的活动延伸到头部的大部分区域。这些发现表明急性未经治疗的精神分裂症患者的大脑功能减退和兴奋性。
We undertook a study of electroencephalograms (EEGs) in 30 right-handed, untreated patients (27.3 .+-. 10.0 years; hebephrenic, 16; paranoid, 12; residual, 2) who fulfilled ICD-9 criteria for schizophrenia and compared them with sex- and age-matched controls by using the percentage of power in six EEG frequency bands calculated as a fraction of total power. T-statistic significance probability mapping (t-SPM) showed that, compared with normal controls, schizophrenics had more slow activity (delta, theta, and alpha 1) in the parieto-occipital regions, and more fast activity (beta 1) in the occipital regions. In contrast, alpha 2 activity decreased strinkingly in the occipital regions and this decreased activity extended over much of the head. These findings were though to indicate both cerebral hypofunction and excitability in acute untreated schizophrenia.