Immunocytochemical component of endocrine cells in pancreatic islets of horses.
Immunocytochemical component of endocrine cells in pancreatic islets of horses.
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马胰岛内分泌细胞的免疫细胞化学成分。
DOI：
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发表时间：
1989
期刊：
影响因子：
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通讯作者：
C. Itakura
中科院分区：
文献类型：
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作者：
H. Furuoka;H. Ito;M. Hamada;T. Suwa;H. Satoh;C. Itakura
用免疫组织化学方法研究了马胰腺左、右、体部4个区域胰岛内分泌细胞的组成：胰左叶、胰右叶、位于十二指肠前曲和十二指肠降部沿着的十二指肠叶和位于门静脉周围的中叶。左叶和中叶的胰岛含有一个由胰岛素细胞包围的胰高血糖素细胞的中央团，一些生长抑素细胞和零星的胰多肽（PP）细胞。另一方面，与其他3个区域相比，十二指肠叶中的胰岛体积较小，并且主要是胰岛素和胰多肽（PP）细胞，但几乎缺乏胰高血糖素细胞。这些结果表明，十二指肠叶起源于腹侧胰腺原基，左、中叶起源于背侧胰腺原基。右叶胰岛细胞的组成和分布与左叶和中叶基本相同，但与十二指肠叶一样，有数个小叶，内含大量PP细胞。
The endocrine cell components in the pancreatic islets of the following 4 pancreatic regions of the horse were investigated by immunohistochemical methods: lobus pancreatis sinister (left lobe); lobus pancreatis dexter (right lobe); and 2 regions of Corpus pancreatis (body), the duodenal lobe which lies along the cranial duodenal flexure and descending duodenum, and the intermediate lobe which is situated around the portal vein. The islets in the left and intermediate lobes contained a central mass of glucagon cells surrounded by insulin cells, a few somatostatin cells and sporadic pancreatic polypeptide (PP) cells. On the other hand, the islets in the duodenal lobe were small in size compared with the other 3 regions, and were predominant in insulin and pancreatic polypeptide (PP) cells, but almost lacked in glucagon cells. These findings suggested that the duodenal lobe was derived from the ventral pancreatic primordium, and the left and intermediate lobes were originated from the dorsal pancreatic primordium. In the right lobe, the composition and distribution of the islet cells were almost the same as those in the left and intermediate lobes, but there were several lobules containing numerous PP cells as seen in the duodenal lobe.