Automated Talairach Atlas labels for functional brain mapping
Automated Talairach Atlas labels for functional brain mapping
复制标题
DOI：
10.1002/1097-0193(200007)10:3
复制
发表时间：
2000-07-01
影响因子：
4.8
通讯作者：
Fox, PT
中科院分区：
文献类型：
--
作者：
Lancaster, JL;Woldorff, MG;Fox, PT
之前引入了一种基于坐标的自动化系统，用于从 1988 年 Talairach Atlas 中检索大脑标签，称为 Talairach Daemon (TD) [Lancaster et al., 1997]。在本研究中，对 TD 系统及其 1988 年 Talairach 图集标签的 3D 数据库进行了功能激活灶标记的测试。将 TD 系统标签与来自 250 多项已发表的功能性脑图研究的作者指定的激活坐标标签以及专家组使用这些激活坐标的子集手动生成的图谱标签进行比较。 TD 系统的自动标记与作者的标签相比效果良好，所有位置的平均标签匹配率为 70% 或更高。对于大多数网站，在 +/-5 毫米的搜索范围内，作者-标签匹配率提高到 90% 以上。使用 M1 嘴部区域（30 名受试者，52 个部位）的个体激活来评估自适应灰质 (GM) 范围搜索实用程序。它在 +/-5 毫米的搜索范围内提供了与 Brodmann 区域标签（BA 4 和 BA 6）87% 的标签匹配率。使用自适应GM范围搜索，TD系统与作者标签的整体匹配度（90%）优于专家组的匹配度（80%）。当与作者对实验的更深入了解结合使用时，TD 系统可为大脑激活焦点提供一致且全面的标签。 TD 系统的其他建议应用包括交互式标记、激活灶的解剖分组、病变缺陷分析和神经解剖学教育。 (C) 2000 Wiley-Liss, Inc.
An automated coordinate-based system to retrieve brain labels from the 1988 Talairach Atlas, called the Talairach Daemon (TD), was previously introduced [Lancaster et al., 1997]. In the present study, the TD system and its 3-D database of labels for the 1988 Talairach atlas were tested for labeling of functional activation foci. TD system labels were compared with author-designated labels of activation coordinates from over 250 published functional brain-mapping studies and with manual atlas-derived labels from an expert group using a subset of these activation coordinates. Automated labeling by the TD system compared well with authors' labels, with a 70% or greater label match averaged over all locations. Author-label matching improved to greater than 90% within a search range of +/-5 mm for most sites. An adaptive grey matter (GM) range-search utility was evaluated using individual activations from the M1 mouth region (30 subjects, 52 sites). It provided an 87% label match to Brodmann area labels (BA 4 & BA 6) within a search range of +/-5 mm. Using the adaptive GM range search, the TD system's overall match with authors' labels (90%) was better than that of the expert group (80%). When used in concert with authors' deeper knowledge of an experiment, the TD system provides consistent and comprehensive labels for brain activation foci. Additional suggested applications of the TD system include interactive labeling, anatomical grouping of activation foci, lesion-deficit analysis, and neuroanatomy education. (C) 2000 Wiley-Liss, Inc.