High prevalence of cardiovascular co-morbidities in patients with symptomatic knee or hand osteoarthritis

High prevalence of cardiovascular co-morbidities in patients with symptomatic knee or hand osteoarthritis
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DOI:
10.3109/03009742.2015.1054875
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发表时间:
2016-01-02
影响因子:
2.1
通讯作者:
Gratacos, J.
Gratacos, J.
中科院分区:
医学4区
文献类型:
--
作者:
Calvet, J.;Orellana, C.;Gratacos, J.

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目的:评估症状性膝或手骨关节炎(OA)患者心血管事件(CVEs)和代谢综合征(MetS)的频率。方法:一项横断面研究进行风湿病学家在初级保健设置。纳入连续出现症状的原发性膝关节或手部OA患者,同时伴有软组织病变的患者作为对照组。记录高血压、糖尿病、肥胖、血脂异常以及由心肌梗死、心绞痛或脑血管疾病组成的cve。结果:共纳入254例OA患者(膝关节OA 184例,手部OA 70例)和254例对照患者。所有OA组中肥胖发生率较高,膝关节OA组中高血压发生率较高。骨性关节炎患者整体和单独的膝关节或手部骨性关节炎组的met发生率明显更高(p
Objectives: To evaluate the frequency of cardiovascular events (CVEs) and metabolic syndrome (MetS) in patients with symptomatic knee or hand osteoarthritis (OA).Method: A cross-sectional study conducted by rheumatologists in a primary care setting. Consecutive symptomatic patients with primary knee or hand OA were included and patients with soft tissue conditions served as the control group. Hypertension, diabetes mellitus, obesity, dyslipidaemia, and CVEs consisting of myocardial infarction, angina, or cerebrovascular disease were recorded.Results: A total of 254 OA patients (184 with knee OA and 70 with hand OA) and 254 control patients were included. The frequency of obesity was higher in all OA groups and hypertension was more frequent in knee OA. MetS was significantly more frequent in patients with OA as a whole group and in knee or hand OA groups separately (p