The Radiochemical and Radiopharmaceutical Applications of Radium
The Radiochemical and Radiopharmaceutical Applications of Radium
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DOI：
10.1515/chem-2016-0011
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发表时间：
2016-01-01
期刊：
影响因子：
2.3
通讯作者：
Mamat, Constantin
中科院分区：
文献类型：
--
作者：
Gott, Matthew;Steinbach, Joerg;Mamat, Constantin
本文综述了镭同位素的化学性质及其在环境监测、分析和医学方面的应用。近年来，镭主要用作示踪剂，研究放射性物质在环境系统中的迁移。追踪矿物和水源中天然存在的镭同位素可以确定来源位置，停留时间和浓度。了解我们的食物和水源中放射性核素的浓度对每个人的健康至关重要，因为α粒子衰变对体内具有高度破坏性。由于这种高放射生物学有效性，人们对使用发射α的放射性核素来制备新的治疗性放射性药物的兴趣增加。从最近的文献中选择的研究提供了这些现代应用的镭同位素的例子。
This review focuses on the chemistry and application of radium isotopes to environmental monitoring, analytical, and medicinal uses. In recent years, radium has been used primarily as a tracer to study the migration of radioactive substances in environmental systems. Tracing the naturally occurring radium isotopes in mineral and water sources allows for the determination of source location, residence time, and concentrations. An understanding of the concentration of radionuclides in our food and water sources is essential to everyone's health as alpha particle decay is highly damaging in vivo. Due to this high radiobiological effectiveness, there is increased interest in using alpha-emitting radionuclides to prepare new, therapeutic radiopharmaceutical drugs. Selected studies from the recent literature are provided as examples of these modern applications of radium isotopes.