Self-Efficacy Mediates the Relationship Between Depressive Symptoms and Medication Adherence Among Hypertensive African Americans
Self-Efficacy Mediates the Relationship Between Depressive Symptoms and Medication Adherence Among Hypertensive African Americans
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DOI：
10.1177/1090198107309459
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发表时间：
2009-02-01
影响因子：
4.2
通讯作者：
Allegrante, John P.
中科院分区：
文献类型：
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作者：
Schoenthaler, Antoinette;Ogedegbe, Gbenga;Allegrante, John P.
许多研究已经记录了抑郁症对坚持推荐治疗的负面影响;然而，对这种关系的机制知之甚少。使用Kenny和Baron的调解分析框架，作者评估了自我效能是否介导了167名高血压非洲裔美国人在初级保健实践中的抑郁症和药物依从性之间的关系。抑郁症状与药物依从性差（β = 0.013，p = 0.036）和自我效能低（β =-0.008，p = 0.023）相关。自我效能与随访时的药物依从性呈负相关（β =-0.612，p <0.001）。当控制自我效能时，抑郁症状和药物依从性之间的关系变得不显著（β = 0.010，p = 0.087）。进一步研究自我效能的中介作用和抑郁症对药物依从性的有害影响的影响进行了讨论。
Many studies have documented the negative effects of depression on adherence to recommended treatment; however, little is known about the mechanism underlying this relationship. Using the Kenny and Baron analytic framework of mediation, the authors assessed whether self-efficacy mediated the relationship between depression and medication adherence in 167 hypertensive African Americans followed in a primary care practice. Depressive symptoms are associated with poor medication adherence (beta = .013, p = .036) and low self-efficacy (beta = -.008 p = .023) Self-efficacy is negatively associated with medication adherence at follow-up (beta = -.612, p < .001). The relationship between depressive symptoms and medication adherence becomes nonsignificant when controlling for self-efficacy (beta = .010, p = .087). Implications for further examination into the mediating role of self-efficacy and the deleterious effect of depression on medication adherence are discussed.