GIARDIASIS - TAMING THIS PERVASIVE PARASITIC INFECTION

GIARDIASIS - TAMING THIS PERVASIVE PARASITIC INFECTION
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DOI:
10.1080/00325481.1995.11946034
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发表时间:
1995-08-01
影响因子:
4.2
通讯作者:
BABB, RR
BABB, RR
中科院分区:
医学4区
文献类型:
--
作者:
BABB, RR

文献摘要

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由贾第虫引起的寄生虫感染可产生严重的、致残的胃肠道症状。暴发与受污染的城市供水和涉及人与人接触的情况有关。免疫功能低下的患者尤其危险。由于粪便的显微镜检查仅在约一半的感染患者中检测到寄生虫,因此使用酶联免疫吸附试验检测贾第虫特异性抗原变得越来越受欢迎。在大多数患者中,使用盐酸奎纳克林(Atabrine)、甲硝唑(Flagyl,Protostat)或两者联合治疗是有效的。
Parasitic infection due to Giardia lamblia can produce severe, disabling gastrointestinal symptoms. Outbreaks have been linked to contaminated municipal water supplies and situations involving person-to-person contact. Immunocompromised patients are especially at risk. Because microscopic examination of stool detects the parasite in only about half of infected patients, use of enzyme-linked immunosorbent assay to detect Giardia-specific antigen is becoming increasingly popular. In most patients, therapy with quinacrine (Atabrine) hydrochloride, metronidazole (Flagyl, Protostat), or a combination of the two is effective.