Percutaneous excimer-laser and excimer-laser-assisted angioplasty of the lower extremities: results of initial clinical trial.
Percutaneous excimer-laser and excimer-laser-assisted angioplasty of the lower extremities: results of initial clinical trial.
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经皮准分子激光和准分子激光辅助下肢血管成形术：初步临床试验的结果。
DOI：
10.1148/radiology.172.2.2526348
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发表时间：
1989
期刊：
影响因子：
19.7
通讯作者：
Forrester,JS
中科院分区：
文献类型：
--
作者：
Litvack,F;Grundfest,WS;Adler,L;Hickey,AE;Segalowitz,J;Hestrin,LB;Mohr,FW;Goldenberg,T;Laudenslager,JS;Forrester,JS
采用308 nm经皮外周准激光血管成形术治疗30例外周血管病变。28例患者行激光辅助球囊血管成形术，2例患者单独行激光血管成形术。31例股腘动脉狭窄和闭塞患者中有24例（77%）获得了急性血管造影和临床成功。7 / 9（78%）狭窄，6 / 7（86%）短（0-5 cm）闭塞，7 / 8（88%）中长（6-10 cm）闭塞，3 / 4（75%）长（11-15 cm）闭塞，1 / 3（33%）极端（大于15 cm）闭塞得到成功治疗。在每个病例中，无法治疗完全闭塞都与未能维持纤维的同轴位置和内膜下通道有关。这些病例证明了安全进行经皮外周准激光或准激光辅助血管成形术的可行性。平均随访9.1个月后，再狭窄的总发生率为29%。数据表明，这些程序可能是有用的治疗周围血管疾病的选定患者。
Percutaneous peripheral excimer-laser angioplasty at 308 nm was used for treatment of 30 patients with peripheral vascular disease. Twenty-eight patients underwent laser-assisted balloon angioplasty, and two patients underwent laser angioplasty alone. Acute angiographic and clinical success was achieved in 24 of 31 (77%) femoropopliteal stenoses and occlusions. Seven of nine (78%) stenoses, six of seven (86%) short (0-5 cm) occlusions, seven of eight (88%) medium-length (6-10 cm) occlusions, three of four (75%) long (11-15 cm) occlusions, and one of three (33%) extreme (greater than 15 cm) occlusions were successfully treated. Inability to treat total occlusions was in each case related to a failure to maintain coaxial position and subintimal passage of the fiber. These cases demonstrate the feasibility of safely performing percutaneous peripheral excimer-laser or excimer-laser-assisted angioplasty. The overall frequency of restenosis after a mean follow-up period of 9.1 months was 29%. The data suggest that these procedures may be useful for the treatment of peripheral vascular disease in selected patients.