Synthesis of 1,2,3,4‐Tetrahydrobenzofuro[3,2‐d]pyrimidines via [4+2] Annulation Reaction of 1,3,5‐Triazinanes and Aurone‐Derived α,β‐Unsaturated Imines.
Synthesis of 1,2,3,4‐Tetrahydrobenzofuro[3,2‐d]pyrimidines via [4+2] Annulation Reaction of 1,3,5‐Triazinanes and Aurone‐Derived α,β‐Unsaturated Imines.
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通过 1,3,5-三嗪和 Aurone 衍生的 α,β-不饱和亚胺的 [4 2] 成环反应合成 1,2,3,4-四氢苯并呋喃[3,2-d]嘧啶
DOI：
10.1002/adsc.202000713
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发表时间：
2020
期刊：
影响因子：
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通讯作者：
Hongbin Zhai
中科院分区：
文献类型：
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作者：
Bin Cheng;Xinping Zhang;Shengxian Zhai;Yixuan He;Qingqing Tao;Hui Li;Jian Wei;Haiyan Sun;Taimin Wang;Hongbin Zhai
研究了1，3，5-三氮杂环与α，β不饱和亚胺的[4+2]环合反应，实现了1，2，3，4-四氢苯并呋喃并[3，2-d]嘧啶的高产率合成。该协议不含催化剂，也不含添加剂。
A [4+2] annulation reaction of 1,3,5‐triazinanes and aurone‐derived α,β‐unsaturated imines has been developed, which enables the synthesis of 1,2,3,4‐tetrahydrobenzofuro[3,2‐d]pyrimidines under thermal conditions in high yields. This protocol is catalyst‐free and additive‐free.