RISK FACTORS ASSOCIATED WITH AMERICAN CUTANEOUS LEISHMANIASIS IN AN ENDEMIC AREA OF BRAZIL
RISK FACTORS ASSOCIATED WITH AMERICAN CUTANEOUS LEISHMANIASIS IN AN ENDEMIC AREA OF BRAZIL
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DOI：
10.1590/s1678-9946201658086
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发表时间：
2016-01-01
期刊：
影响因子：
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通讯作者：
BRAYNER, Fábio André
中科院分区：
文献类型：
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作者：
ARAUJO, Alberon Ribeiro de;PORTELA, Nairomberg Cavalcanti;BRAYNER, Fábio André
巴西是世界上利什曼病病例数最多的五个国家之一，该国所有地区都有利什曼病病例。东北地区每年的病例数仍然较高，在伯南布哥州，34%的城市是这种疾病的地方病。病媒、宿主和病原的多样性，与社会经济和环境条件有关，产生了可以改变美国皮肤利什曼病行为的因素。因此，本研究的目的是确定与巴西廷巴巴市美国皮肤利什曼病相关的危险因素。进行了病例对照研究。采用一份有效的问卷进行数据收集。该研究包括58例病例和174例对照，并在Oswaldo Cruz基金会（FIOCRUZ）进行血清学诊断。我们的研究结果表明，一些因素与美国皮肤利什曼病有关：生物学（性别）、经济（工作活动、离家时间和供水）和家居环境（动物的存在）。在我们的研究中，这些变量与利什曼病的关联与不稳定的住房条件和贫困有关，这些参数可以通过管理来预防该地区的疾病。
Brazil is among the top five countries worldwide regarding the number of cases of leishmaniasis, which are present in all of the regions of the country. The northeastern region continues to have higher numbers of cases every year and in the state of Pernambuco, 34% of the municipalities are endemic for this disease. The diversity of vectors, reservoirs and etiological agents, in association with socioeconomic and environmental conditions, gives rise to factors that can modify the behavior of American cutaneous leishmaniasis. Consequently, the aim of the present study was to determine the risk factors associated with American cutaneous leishmaniasis in the municipality of Timbauba, Brazil. A case-control study was conducted. A validated questionnaire was used for data collection. The study included 58 cases and 174 controls, and they were serologically diagnosed at the Oswaldo Cruz Foundation (FIOCRUZ). Our results showed that some factors were associated with American cutaneous leishmaniasis: biological (gender), economic (work activity, hours spent away from home and water supply) and peridomestic (presence of animals). In our study, the associations of these variables with leishmaniasis were linked to precarious housing conditions and poverty, which are parameters that can be managed in order to prevent the disease in this region.