Cardiovascular reactivity in patients with essential or renal hypertension under standardized mental stress
Cardiovascular reactivity in patients with essential or renal hypertension under standardized mental stress
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DOI：
10.1080/10641960701500414
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发表时间：
2007-07-01
影响因子：
12.3
通讯作者：
Weber, Cora
中科院分区：
文献类型：
--
作者：
Deter, Hans-Christian;Wolf, Christiane;Weber, Cora
导言。与血压正常者相比，高血压患者对精神压力的反应更强烈。这可能与应对压力的类型有关，也可能与疾病相关的反应性增加有关。我们研究的目的是检查原发性高血压和继发性高血压患者对内在压力的反应是否不同。方法：研究方法。对17例高血压病患者(EH)、9例肾性高血压(RH)患者和22例血压正常者(N)进行了心理应激状态下的心理生理检查。测量血压(BP)、心率(HR)和皮肤电活动(EDA)。结果。两组高血压病患者对应激的血压反应与对照组不同，但差异无统计学意义。在矩阵测试中，原发性高血压患者的心率和收缩压乘积显著高于肾性高血压患者(EH中位数：13344；RH中位数：12154.5；P=0.04)。这也适用于实验后静息阶段EDA的自发涨落次数(EH。中位数：3.2；相对湿度。中位数：1.3；p=0.01)。结论。结果表明，不仅高血压水平高，而且交感神经张力对精神压力的血压反应也有影响。由于非常不同的(可能是心理触发的)条件，原发性高血压在精神压力下比肾性高血压导致更强的心血管反应。
Introduction. Patients with essential hypertension react more strongly to mental stress than normotensives. This may be related to the type of stress coping or to increased reactivity associated with the disease. The aim of our study was to examine whether patients with essential or secondary hypertension differ in their reaction to inental stress. Methods. Seventeen patients with essential hypertension (EH), 9 patients with renal hypertension (RH), and 22 normotensive controls (N) with no circulatory disorders were subjected to a psychophysiological examination under mental stress. Blood pressure (BP), heart rate (HR) and electrodermal activity, (EDA) were measured. Results. The two hypertensive groups differed in their BP reaction to inental stress from the control group but not from each other. The product of heart rate and systolic blood pressure during the matrix test was significantly higher in essential than renal hypertensives (EH median: 13344; RH median: 12154.5; p = 0.04). This also holds true for the number of spontaneous fluctuations of EDA in the resting phase after the experiment (EH. median: 3.2; RH. median: 1.3; p = 0.01). Conclusion. The results suggest that not only a high blood pressure level but also the sympathetic nervous tone are responsible for the blood pressure response to mental stress. Due to very different (perhaps psychosocially triggered) conditions, essential hypertension leads to a stronger cardiovascular reaction under mental stress than renal hypertension.