The traceless Staudinger ligation for indirect 18F-radiolabelling
The traceless Staudinger ligation for indirect 18F-radiolabelling
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DOI：
10.1039/c0ob00564a
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发表时间：
2011-01-01
影响因子：
3.2
通讯作者：
Gouverneur, Veronique
中科院分区：
文献类型：
--
作者：
Carroll, Laurence;Boldon, Sophie;Gouverneur, Veronique
膦取代硫酯与F-18-氟乙肼的Staudinger连接已成功地用于获得F-18标记的分子，放化产率高于95%；Staudinger放射性连接的第一个氟变体已得到验证。
The Staudinger ligation of phosphine-substituted thioesters with F-18-fluoroethylazide has been successfully applied to access F-18-labelled molecules in radiochemical yields superior to 95%; the first fluorous variant of a Staudinger radio-ligation has been validated.