Risk for Poor Post-Operative Quality of Life Among Wearable Use Subgroups in an All of Us Research Cohort
Risk for Poor Post-Operative Quality of Life Among Wearable Use Subgroups in an All of Us Research Cohort
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我们所有人研究队列中可穿戴设备亚组术后生活质量差的风险
DOI：
10.1142/9789811270611_0004
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发表时间：
2022
影响因子：
--
通讯作者：
Casey Overby Taylor
中科院分区：
文献类型：
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作者：
Nidhi Soley;Shanshan Song;N. Flaks;Casey Overby Taylor
本研究的目的是建立和评估一个预测模型的性能，术后恢复状态的生活质量的个人经历了各种手术类型之间的测量。此外，我们还评估了两个亚组（高度一致和中度一致的可穿戴设备用户）的模型性能。研究变量来源于具有8种手术类型之一的一组个体的电子健康记录、问卷和可穿戴设备，并且是NIH All of Us研究计划的一部分。通过多因素分析，发现高虚弱指数（OR 1.69，95% 1.05-7.22，p<0.006）和高龄（OR 1.76，95% 1.55-4.08，p<0.024）是术后恢复不良的驱动危险因素。我们的逻辑回归模型包括15个变量，其中5个包括可穿戴设备数据。在可穿戴使用亚组中，该模型对高可穿戴用户的准确性更高（81%）。研究结果表明，使用可穿戴措施来评估虚弱程度的模型具有潜力，可以告知临床医生患者面临手术结果不佳的风险。我们的模型在多种手术类型中具有高准确性，并且在可穿戴使用中对可变一致性具有鲁棒性。
The objective of this research was to build and assess the performance of a prediction model for postoperative recovery status measured by quality of life among individuals experiencing a variety of surgery types. In addition, we assessed the performance of the model for two subgroups (high and moderately consistent wearable device users). Study variables were derived from the electronic health records, questionnaires, and wearable devices of a cohort of individuals with one of 8 surgery types and that were part of the NIH All of Us research program. Through multivariable analysis, high frailty index (OR 1.69, 95% 1.05-7.22, p<0.006), and older age (OR 1.76, 95% 1.55-4.08, p<0.024) were found to be the driving risk factors of poor recovery post-surgery. Our logistic regression model included 15 variables, 5 of which included wearable device data. In wearable use subgroups, the model had better accuracy for high wearable users (81%). Findings demonstrate the potential for models that use wearable measures to assess frailty to inform clinicians of patients at risk for poor surgical outcomes. Our model performed with high accuracy across multiple surgery types and were robust to variable consistency in wearable use.
DOI：
10.1056/nejmsr1809937
发表时间：
2019-08-15
期刊：
The New England journal of medicine
影响因子：
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作者：
All of Us Research Program Investigators;Denny JC;Rutter JL;Goldstein DB;Philippakis A;Smoller JW;Jenkins G;Dishman E
通讯作者：
Dishman E