Cupredoxins--a study of how proteins may evolve to use metals for bioenergetic processes.

Cupredoxins--a study of how proteins may evolve to use metals for bioenergetic processes.
复制标题

DOI:
10.1039/c0mt00061b
复制
发表时间:
2011-03
期刊:
Metallomics : integrated biometal science
影响因子:
--
通讯作者:
Davidson VL
Davidson VL
中科院分区:
其他
文献类型:
--
作者:
Choi M;Davidson VL

文献摘要

参考文献

被引文献

相似文献

铜氧毒素是一种含有I型铜中心的小蛋白质,在自然界中无处不在。它们的功能是蛋白质之间的电子传递载体。本文综述了天然铜氧毒素的结构和性质,以及通过位点定向诱变修饰的铜氧毒素,说明了这些蛋白质如何进化到特异性结合铜,为特定的氧化还原伙伴开发识别位点,调整氧化还原电位的特定功能,并允许有效的电子通过蛋白质基质转移。这与对金属在能量代谢、呼吸和光合作用中的作用的一般理解有关。
Cupredoxins are small proteins that contain type I copper centers, which are ubiquitous in nature. They function as electron transfer shuttles between proteins. This review of the structure and properties of native cupredoxins, and those modified by site-directed mutagenesis, illustrates how these proteins may have evolved to specifically bind copper, develop recognition sites for specific redox partners, tune redox potential for a particular function, and allow for efficient electron transfer through the protein matrix. This is relevant to the general understanding of the roles of metals in energy metabolism, respiration and photosynthesis.
DOI: 10.1021/bi971353m
发表时间: 1997-10-21
期刊: BIOCHEMISTRY
影响因子: 2.9
作者:
Davidson, VL;Jones, LH;Hosler, JP
通讯作者: Hosler, JP
DOI: 10.1021/bi900836h
发表时间: 2009-10-06
期刊: Biochemistry
影响因子: 2.9
作者:
Choi M;Sukumar N;Liu A;Davidson VL
通讯作者: Davidson VL
DOI: 10.1021/bi952854f
发表时间: 1996-06-25
期刊: BIOCHEMISTRY
影响因子: 2.9
作者:
Davidson, VL;Jones, LH
通讯作者: Jones, LH
DOI: 10.1021/ja029699u
发表时间: 2003-07-23
影响因子: 15
作者:
Berry, SM;Ralle, M;Lu, Y
通讯作者: Lu, Y
DOI: 10.1021/bi049634z
发表时间: 2004-07-27
期刊: BIOCHEMISTRY
影响因子: 2.9
作者:
Carrell, CJ;Sun, DP;Mathews, FS
通讯作者: Mathews, FS