Prevalence of Diabetes among Men and Women in China
Prevalence of Diabetes among Men and Women in China
复制标题
DOI：
10.1056/nejmoa0908292
复制
发表时间：
2010-03-25
影响因子：
158.5
通讯作者：
He, Jiang
中科院分区：
文献类型：
--
作者：
Yang, Wenying;Lu, Juming;He, Jiang
背景
由于中国生活方式的快速变化，人们担心糖尿病可能会流行。我们在2007年6月至2008年5月进行了一项全国性研究，以评估中国成年人糖尿病的患病率。
方法
来自14个省和直辖市的46239名20岁及以上具有全国代表性的成年人参与了这项研究。参与者禁食过夜后，接受口服葡萄糖耐量试验，并测量空腹和2小时血糖水平，以识别未确诊的糖尿病和糖尿病前期（即空腹血糖受损或葡萄糖耐量受损）。先前已确诊的糖尿病是根据自我报告确定的。
结果
总的糖尿病（包括先前已确诊的糖尿病和先前未确诊的糖尿病）和糖尿病前期的年龄标准化患病率分别为9.7%（男性为10.6%，女性为8.8%）和15.5%（男性为16.1%，女性为14.9%），分别对应9240万成年糖尿病患者（男性5020万，女性4220万）和14820万成年糖尿病前期患者（男性7610万，女性7210万）。糖尿病患病率随年龄增长而增加（20 - 39岁、40 - 59岁和≥60岁人群中分别为3.2%、11.5%和20.4%），也随体重增加而增加（体重指数[体重（千克）除以身高（米）的平方]＜18.5、18.5 - 23.9、24.0 - 27.9和≥30.0的人群中分别为4.5%、7.6%、12.8%和18.5%）。城市居民的糖尿病患病率高于农村居民（11.4%对8.2%）。单纯葡萄糖耐量受损的患病率高于单纯空腹血糖受损的患病率（男性中分别为11.0%对3.2%，女性中分别为10.9%对2.2%）。
结论
这些结果表明糖尿病已成为中国的一个重大公共卫生问题，需要制定针对糖尿病预防和治疗的策略。
BACKGROUNDBecause of the rapid change in lifestyle in China, there is concern that diabetes may become epidemic. We conducted a national study from June 2007 through May 2008 to estimate the prevalence of diabetes among Chinese adults.METHODSA nationally representative sample of 46,239 adults, 20 years of age or older, from 14 provinces and municipalities participated in the study. After an overnight fast, participants underwent an oral glucose-tolerance test, and fasting and 2-hour glucose levels were measured to identify undiagnosed diabetes and prediabetes (i.e., impaired fasting glucose or impaired glucose tolerance). Previously diagnosed diabetes was determined on the basis of self-report.RESULTSThe age-standardized prevalences of total diabetes ( which included both previously diagnosed diabetes and previously undiagnosed diabetes) and prediabetes were 9.7% (10.6% among men and 8.8% among women) and 15.5% (16.1% among men and 14.9% among women), respectively, accounting for 92.4 million adults with diabetes (50.2 million men and 42.2 million women) and 148.2 million adults with prediabetes (76.1 million men and 72.1 million women). The prevalence of diabetes increased with increasing age (3.2%, 11.5%, and 20.4% among persons who were 20 to 39, 40 to 59, and >= 60 years of age, respectively) and with increasing weight (4.5%, 7.6%, 12.8%, and 18.5% among persons with a body-mass index [ the weight in kilograms divided by the square of the height in meters] of = 30.0, respectively). The prevalence of diabetes was higher among urban residents than among rural residents (11.4% vs. 8.2%). The prevalence of isolated impaired glucose tolerance was higher than that of isolated impaired fasting glucose (11.0% vs. 3.2% among men and 10.9% vs. 2.2% among women).CONCLUSIONSThese results indicate that diabetes has become a major public health problem in China and that strategies aimed at the prevention and treatment of diabetes are needed.