Genetic Heterogeneity and Recombination in Human Type 2 Astroviruses
Genetic Heterogeneity and Recombination in Human Type 2 Astroviruses
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DOI：
10.1128/jcm.02102-12
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发表时间：
2012-11-01
影响因子：
9.4
通讯作者：
Martella, V.
中科院分区：
文献类型：
--
作者：
De Grazia, S.;Medici, M. C.;Martella, V.
人类星状病毒 (HAstV) 2、2c 和 2d 型的新谱系已被鉴定。对基因组 3' 端进行测序后，发现 2c 型和 2d 型 HAstV 是开放阅读框 1b (ORF1b)-ORF2 重组体，其中 ORF1b 分别源自 3 型和 1 型 HAstV。还鉴定出 ORF2 谱系重组菌株 2c/2b。
Novel lineages of human astrovirus (HAstV) types 2, 2c, and 2d have been identified. Upon sequencing of the 3' end of the genome, the type 2c and 2d HAstVs were found to be open reading frame 1b (ORF1b)-ORF2 recombinant, with ORF1b being derived from type 3 and type 1 HAstVs, respectively. An ORF2 interlineage recombinant strain, 2c/2b, was also identified.