Electrochemical Detection in a Paper-Based Separation Device
Electrochemical Detection in a Paper-Based Separation Device
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DOI：
10.1021/ac902647r
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发表时间：
2010-02-01
影响因子：
7.4
通讯作者：
Kubota, Lauro Tatsuo
中科院分区：
文献类型：
--
作者：
Carvalhal, Rafaela Fernanda;Kfouri, Marta Simao;Kubota, Lauro Tatsuo
开发并评价了具有安培检测的微流控纸基分离装置的原型。使用光刻法在聚酯上制造金电化学微电池，并将该微电池耦合到发生色谱分离的纸条上。通过对混合物中尿酸和抗坏血酸的分离和定量，证明了该装置的性能。该方法提供了一种分析替代化合物的测定，其中低成本和简单是必不可少的。
Prototypes of microfluidic paper-based separation devices with amperometric detection were developed and evaluated. Photolithography was used to make a gold electrochemical microcell on polyester and that microcell was coupled to a strip of paper where a chromatographic separation occurs. The device performance was demonstrated with the separation and quantification of uric and ascorbic acid in mixtures. The method provides an analytical alternative for the determination of compounds where low cost and simplicity are essential.